The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	buspirone
Synonyms	8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione buspirone Buspirone buspironum 8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dione 8-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione buspirona C21H31N5O2
ID	http://purl.obolibrary.org/obo/CHEBI_3223
AHFScode	28:24.92
ATCCode	N05BE01
blocks	http://purl.obolibrary.org/obo/dinto_2804
CASRN	36505-84-7
DBBrand	ansiced censpar buspinol lucelan buspar narol ansial anxiron bespar travin buspimen buspisal axoren
DBname	buspirone
DBSynonym	buspironum [inn-latin] buspirone hcl buspirona [inn-spanish]
Definition	An azaspiro compound that has formula C21H31N5O2.
has effect	http://purl.obolibrary.org/obo/OAE_0000785 http://purl.obolibrary.org/obo/OAE_0000395 http://purl.obolibrary.org/obo/OAE_0000303 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000630 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000335 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0001186 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0001489 http://purl.obolibrary.org/obo/OAE_0001360 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000333 http://purl.obolibrary.org/obo/OAE_0000250 http://purl.obolibrary.org/obo/OAE_0001339 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001515 http://purl.obolibrary.org/obo/OAE_0000309 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000586 http://purl.obolibrary.org/obo/OAE_0000510 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000842 http://purl.obolibrary.org/obo/OAE_0000643 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000894 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000038 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000780 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0001336 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000275 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000470 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000313 http://purl.obolibrary.org/obo/OAE_0000534
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2804 http://purl.obolibrary.org/obo/dinto_1166
has role	http://purl.obolibrary.org/obo/CHEBI_35474 http://purl.obolibrary.org/obo/CHEBI_35941 http://purl.obolibrary.org/obo/CHEBI_35717
InChI	InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2
InChIKey	InChIKey=QWCRAEMEVRGPNT-UHFFFAOYSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_1440
is metabolised by	http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1956
label	buspirone
may interact with	http://purl.obolibrary.org/obo/CHEBI_9948 http://purl.obolibrary.org/obo/CHEBI_9943 http://purl.obolibrary.org/obo/CHEBI_101278 http://purl.obolibrary.org/obo/dinto_DB00726 http://purl.obolibrary.org/obo/CHEBI_7494 http://purl.obolibrary.org/obo/dinto_DB00780 http://purl.obolibrary.org/obo/CHEBI_9654 http://purl.obolibrary.org/obo/dinto_DB00582 http://purl.obolibrary.org/obo/CHEBI_3732 http://purl.obolibrary.org/obo/CHEBI_45367 http://purl.obolibrary.org/obo/dinto_DB01247 http://purl.obolibrary.org/obo/dinto_DB00752 http://purl.obolibrary.org/obo/CHEBI_63620 http://purl.obolibrary.org/obo/dinto_DB00199 http://purl.obolibrary.org/obo/dinto_DB00503 http://purl.obolibrary.org/obo/CHEBI_31739 http://purl.obolibrary.org/obo/CHEBI_10124 http://purl.obolibrary.org/obo/CHEBI_28077 http://purl.obolibrary.org/obo/dinto_DB00976 http://purl.obolibrary.org/obo/dinto_DB06700
prefixIRI	obo2:CHEBI_3223
prefLabel	buspirone
related with	http://purl.obolibrary.org/obo/dinto_1166
SMILES	O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)C1=NC=CC=N1 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1
Synonym	8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione buspirone Buspirone buspironum 8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dione 8-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione buspirona C21H31N5O2
xref	CASRN:36505-84-7 KEGG DRUG:D07593 Patent:DE2057845 Wikipedia:Buspirone ChemSpider:2383 PharmGKB:PA448689 Patent:US3717634 Drugs.com:http://www.drugs.com/buspirone.html RxList:http://www.rxlist.com/cgi/generic/buspir.htm Guide To Pharmacology:36 PubChem Substance:46508113 KEGG COMPOUND:C06861 Drugs Product Database (DPD):2242149 ChEMBL:103599 Beilstein:964904 ChEBI:3223 Wikipedia:http://en.wikipedia.org/wiki/Buspirone DrugBank:DB00490 PubChem Compound:2477 National Drug Code Directory:0378-1140-01 IUPHAR:36
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_3223	EFO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223	OBA	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223	NIFSTD	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223	ODNAE	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_3223	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_3223	OBA	LOOM
http://purl.obolibrary.org/obo/NCIT_C62013	BERO	LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Buspirone	APAONTO	LOOM
http://purl.obolibrary.org/obo/MESH_D002065	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_3223	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_3223	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_3223	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_3223	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_3223	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_3223	NIFSTD	LOOM
http://purl.obolibrary.org/obo/CHEBI_3223	ODNAE	LOOM
http://purl.bioontology.org/ontology/CSP/4000-0133	CRISP	LOOM
http://purl.bioontology.org/ontology/VANDF/4019646	VANDF	LOOM
http://purl.jp/bio/4/id/200906092539845452	IOBC	LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass4f27d3a3_7013_4343_bce6_115918d87f26	WWECA	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#2244	OCHV	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62013	NCIT	LOOM
http://www.drugbank.ca/drugs/DB00490	FTC	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387523009	SNOMEDCT	LOOM
http://www.co-ode.org/ontologies/galen#Buspirone	GALEN	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016975	PMAPP-PMO	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147739	ODAE	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.847.885.120	RH-MESH	LOOM
http://stirdf.jst.go.jp/id/200907031039222429	IOBC	LOOM
http://purl.obolibrary.org/obo/OMIT_0003414	OMIT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.742.120	RH-MESH	LOOM
https://go.drugbank.com/drugs/DB00490	MDM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.885.120	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU063033	LOINC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0006462	OCHV	LOOM
http://purl.bioontology.org/ontology/ATC/N05BE01	ATC	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147739	NDFRT	LOOM
http://purl.bioontology.org/ontology/SNMI/C-64210	SNMI	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002065	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/LP17859-7	LOINC	LOOM
http://purl.bioontology.org/ontology/RXNORM/1827	RXNORM	LOOM
http://purl.bioontology.org/ontology/MESH/D002065	MESH	LOOM
http://purl.bioontology.org/ontology/NDDF/004586	NDDF	LOOM
http://purl.bioontology.org/ontology/RCD/x01BH	RCD	LOOM