The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	quinidine
Synonyms	6-methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol Kinidin pitayine (S)-(6-methoxyquinolin-4-yl)((2R,5R)-5-vinylquinuclidin-2-yl)methanol quinidine Chinidin (9S)-6'-methoxycinchonan-9-ol (8R,9S)-quinidine chinidinum conquinine (+)-quinidine (S)-(6-Methoxy-quinolin-4-yl)-((2R,5R)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol alpha-(6-methoxy-4-quinolyl)-5-vinyl-2-quinuclidinemethanol quinidina (R)-(6-methoxyquinolin-4-yl)((3S,4R,7S)-3-vinylquinuclidin-7-yl)methanol Conchinin beta-quinine Quinidine C20H24N2O2 CIN-QUIN
ID	http://purl.obolibrary.org/obo/CHEBI_28593
AHFScode	24:04.04.04
altId	CHEBI:595841 CHEBI:355477 CHEBI:529982 CHEBI:127150 CHEBI:8719 CHEBI:604323 CHEBI:26494 CHEBI:597286
ATCCode	C01BA01
CASRN	56-54-2
DBBrand	quinaglute dura-tabs conchinine quinatime quinalan duraquin cin-quin quinate apo-quinidine pitayine quinora conchinin quinidex novoquinidin quinaglute chinidin kinidin quindine coccinine conquinine cardioquin quinidex extentabs pitayin quinicardine quin-release biquin durules quinact
DBname	quinidine
DBSynonym	quinidine sulfate
Definition	A cinchona alkaloid consisting of cinchonine with the hydrogen at the 6-position of the quinoline ring substituted by methoxy.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0001297 http://purl.obolibrary.org/obo/OAE_0001059 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000589 http://purl.obolibrary.org/obo/OAE_0000573 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000882 http://purl.obolibrary.org/obo/OAE_0000630 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000659 http://purl.obolibrary.org/obo/OAE_0000198 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000411 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000577 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0001012 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000333 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0001538 http://purl.obolibrary.org/obo/OAE_0001055 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0001234 http://purl.obolibrary.org/obo/OAE_0000851 http://purl.obolibrary.org/obo/OAE_0000802 http://purl.obolibrary.org/obo/OAE_0001057 http://purl.obolibrary.org/obo/OAE_0001295 http://purl.obolibrary.org/obo/OAE_0001068 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000510 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0002122 http://purl.obolibrary.org/obo/OAE_0001742 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000647 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000491 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000487 http://purl.obolibrary.org/obo/OAE_0001147 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001291 http://purl.obolibrary.org/obo/OAE_0000565 http://purl.obolibrary.org/obo/OAE_0001345 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000881 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0001366 http://purl.obolibrary.org/obo/OAE_0000480 http://purl.obolibrary.org/obo/OAE_0001364 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000049 http://purl.obolibrary.org/obo/OAE_0000506
has pharmacological target	http://purl.obolibrary.org/obo/dinto_1670
has role	http://purl.obolibrary.org/obo/CHEBI_38070 http://purl.obolibrary.org/obo/CHEBI_48876 http://purl.obolibrary.org/obo/CHEBI_23924 http://purl.obolibrary.org/obo/CHEBI_38633 http://purl.obolibrary.org/obo/CHEBI_37890 http://purl.obolibrary.org/obo/CHEBI_38068
InChI	InChI=1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19+,20-/m0/s1
InChIKey	InChIKey=LOUPRKONTZGTKE-LHHVKLHASA-N
induces	http://purl.obolibrary.org/obo/dinto_0901
inhibits	http://purl.obolibrary.org/obo/dinto_1670 http://purl.obolibrary.org/obo/dinto_2814 http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_1979 http://purl.obolibrary.org/obo/dinto_1970 http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_3187 http://purl.obolibrary.org/obo/dinto_0887 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2739 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0269 http://purl.obolibrary.org/obo/dinto_2019 http://purl.obolibrary.org/obo/dinto_1987 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_3489 http://purl.obolibrary.org/obo/dinto_2789 http://purl.obolibrary.org/obo/dinto_3531 http://purl.obolibrary.org/obo/dinto_0465
is metabolised by	http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_0293 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1956 http://purl.obolibrary.org/obo/dinto_1221
is transported by	http://purl.obolibrary.org/obo/dinto_1970 http://purl.obolibrary.org/obo/dinto_1440
label	quinidine
may interact with	http://purl.obolibrary.org/obo/dinto_DB01551 http://purl.obolibrary.org/obo/dinto_DB00906 http://purl.obolibrary.org/obo/CHEBI_32250 http://purl.obolibrary.org/obo/CHEBI_102524 http://purl.obolibrary.org/obo/CHEBI_9948 http://purl.obolibrary.org/obo/CHEBI_9943 http://purl.obolibrary.org/obo/CHEBI_4551 http://purl.obolibrary.org/obo/CHEBI_5280 http://purl.obolibrary.org/obo/CHEBI_8107 http://purl.obolibrary.org/obo/CHEBI_4317 http://purl.obolibrary.org/obo/CHEBI_16714 http://purl.obolibrary.org/obo/CHEBI_71940 http://purl.obolibrary.org/obo/CHEBI_127342 http://purl.obolibrary.org/obo/CHEBI_41774 http://purl.obolibrary.org/obo/dinto_DB01142 http://purl.obolibrary.org/obo/dinto_DB00794 http://purl.obolibrary.org/obo/dinto_DB00541 http://purl.obolibrary.org/obo/CHEBI_102166 http://purl.obolibrary.org/obo/CHEBI_37924 http://purl.obolibrary.org/obo/dinto_DB00243 http://purl.obolibrary.org/obo/CHEBI_9939 http://purl.obolibrary.org/obo/dinto_DB00306 http://purl.obolibrary.org/obo/dinto_DB00344 http://purl.obolibrary.org/obo/CHEBI_10127 http://purl.obolibrary.org/obo/CHEBI_101278 http://purl.obolibrary.org/obo/dinto_DB01355 http://purl.obolibrary.org/obo/dinto_DB01397 http://purl.obolibrary.org/obo/CHEBI_156095 http://purl.obolibrary.org/obo/CHEBI_42944 http://purl.obolibrary.org/obo/dinto_DB00540 http://purl.obolibrary.org/obo/CHEBI_70746 http://purl.obolibrary.org/obo/CHEBI_63611 http://purl.obolibrary.org/obo/CHEBI_8874 http://purl.obolibrary.org/obo/CHEBI_47499 http://purl.obolibrary.org/obo/CHEBI_61049 http://purl.obolibrary.org/obo/dinto_DB00726 http://purl.obolibrary.org/obo/CHEBI_102216 http://purl.obolibrary.org/obo/CHEBI_47780 http://purl.obolibrary.org/obo/CHEBI_8069 http://purl.obolibrary.org/obo/dinto_DB01336 http://purl.obolibrary.org/obo/CHEBI_53289 http://purl.obolibrary.org/obo/dinto_DB06287 http://purl.obolibrary.org/obo/dinto_DB00312 http://purl.obolibrary.org/obo/dinto_DB00342 http://purl.obolibrary.org/obo/CHEBI_53766 http://purl.obolibrary.org/obo/CHEBI_63632 http://purl.obolibrary.org/obo/CHEBI_3699 http://purl.obolibrary.org/obo/CHEBI_45652 http://purl.obolibrary.org/obo/CHEBI_6780 http://purl.obolibrary.org/obo/dinto_DB01354 http://purl.obolibrary.org/obo/CHEBI_133809 http://purl.obolibrary.org/obo/CHEBI_9566 http://purl.obolibrary.org/obo/CHEBI_7731 http://purl.obolibrary.org/obo/CHEBI_51364 http://purl.obolibrary.org/obo/dinto_DB01167 http://purl.obolibrary.org/obo/dinto_DB00570 http://purl.obolibrary.org/obo/CHEBI_63115 http://purl.obolibrary.org/obo/CHEBI_63598 http://purl.obolibrary.org/obo/CHEBI_10125 http://purl.obolibrary.org/obo/CHEBI_7565 http://purl.obolibrary.org/obo/CHEBI_9654 http://purl.obolibrary.org/obo/dinto_DB00582 http://purl.obolibrary.org/obo/dinto_DB00237 http://purl.obolibrary.org/obo/dinto_DB01558 http://purl.obolibrary.org/obo/dinto_DB01352 http://purl.obolibrary.org/obo/dinto_DB00365 http://purl.obolibrary.org/obo/dinto_DB00514 http://purl.obolibrary.org/obo/CHEBI_75988 http://purl.obolibrary.org/obo/CHEBI_10119 http://purl.obolibrary.org/obo/CHEBI_6758 http://purl.obolibrary.org/obo/CHEBI_9635 http://purl.obolibrary.org/obo/CHEBI_8466 http://purl.obolibrary.org/obo/CHEBI_3720 http://purl.obolibrary.org/obo/CHEBI_7907 http://purl.obolibrary.org/obo/dinto_DB01378 http://purl.obolibrary.org/obo/CHEBI_3732 http://purl.obolibrary.org/obo/CHEBI_480999 http://purl.obolibrary.org/obo/CHEBI_9622 http://purl.obolibrary.org/obo/CHEBI_64355 http://purl.obolibrary.org/obo/CHEBI_2914 http://purl.obolibrary.org/obo/CHEBI_9398 http://purl.obolibrary.org/obo/CHEBI_10033 http://purl.obolibrary.org/obo/CHEBI_9467 http://purl.obolibrary.org/obo/CHEBI_32315 http://purl.obolibrary.org/obo/CHEBI_63628 http://purl.obolibrary.org/obo/dinto_DB01351 http://purl.obolibrary.org/obo/CHEBI_45716 http://purl.obolibrary.org/obo/CHEBI_31236 http://purl.obolibrary.org/obo/dinto_DB01396 http://purl.obolibrary.org/obo/CHEBI_70707 http://purl.obolibrary.org/obo/dinto_DB01118 http://purl.obolibrary.org/obo/dinto_DB00199 http://purl.obolibrary.org/obo/CHEBI_4513 http://purl.obolibrary.org/obo/dinto_DB00503 http://purl.obolibrary.org/obo/dinto_DB01369 http://purl.obolibrary.org/obo/CHEBI_2639 http://purl.obolibrary.org/obo/dinto_DB01320 http://purl.obolibrary.org/obo/dinto_DB01026 http://purl.obolibrary.org/obo/CHEBI_8428 http://purl.obolibrary.org/obo/CHEBI_32139 http://purl.obolibrary.org/obo/CHEBI_71226 http://purl.obolibrary.org/obo/CHEBI_28077 http://purl.obolibrary.org/obo/CHEBI_47781 http://purl.obolibrary.org/obo/dinto_DB01346 http://purl.obolibrary.org/obo/dinto_DB01353 http://purl.obolibrary.org/obo/CHEBI_195280 http://purl.obolibrary.org/obo/dinto_DB00220 http://purl.obolibrary.org/obo/dinto_DB01208 http://purl.obolibrary.org/obo/dinto_DB01341 http://purl.obolibrary.org/obo/CHEBI_9073 http://purl.obolibrary.org/obo/dinto_DB06274 http://purl.obolibrary.org/obo/CHEBI_46295 http://purl.obolibrary.org/obo/dinto_DB00976 http://purl.obolibrary.org/obo/CHEBI_2666
prefixIRI	obo2:CHEBI_28593
prefLabel	quinidine
related with	http://purl.obolibrary.org/obo/dinto_3582
SMILES	[H][C@@]1(C[C@@H]2CC[N@]1C[C@@H]2C=C)[C@@H](O)c1ccnc2ccc(OC)cc12 [H][C@@]12CCN(C[C@@H]1C=C)[C@]([H])(C2)[C@@H](O)C1=C2C=C(OC)C=CC2=NC=C1
Synonym	6-methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol Kinidin pitayine (S)-(6-methoxyquinolin-4-yl)((2R,5R)-5-vinylquinuclidin-2-yl)methanol quinidine Chinidin (9S)-6'-methoxycinchonan-9-ol (8R,9S)-quinidine chinidinum conquinine (+)-quinidine (S)-(6-Methoxy-quinolin-4-yl)-((2R,5R)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol alpha-(6-methoxy-4-quinolyl)-5-vinyl-2-quinuclidinemethanol quinidina (R)-(6-methoxyquinolin-4-yl)((3S,4R,7S)-3-vinylquinuclidin-7-yl)methanol Conchinin beta-quinine Quinidine C20H24N2O2 CIN-QUIN
xref	DrugBank:DB00908 CASRN:56-54-2 National Drug Code Directory:53489-459-02 ChemSpider:389880 KEGG DRUG:D08458 ChEMBL:15270556 CiteXplore:445303 Guide To Pharmacology:2342 ChEMBL:18788725 PharmGKB:PA451209 KEGG COMPOUND:C06527 ChEMBL:15225721 IUPHAR:2342 ChEMBL:17870541 ChEMBL:18395298 Reaxys:91866 ChEMBL:12477351 ChEBI:28593 RxList:http://www.rxlist.com/cgi/generic/quinidine.htm CiteXplore:17249648 Beilstein:91866 ChEMBL:17228875 Drugs Product Database (DPD):497525 ChEMBL:12699389 ChEMBL:17132069 Drugs.com:http://www.drugs.com/cdi/quinidine-gluconate-controlled-release-tablets.html PubChem Compound:441074 ChEMBL:14971904 ChEMBL:16570918 ChEMBL:18324762 PubChem Substance:46505356 NIST Chemistry WebBook:56-54-2 Wikipedia:http://en.wikipedia.org/wiki/Quinidine
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_28593	DOID	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28593	EFO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28593	FYPO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28593	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28593	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28593	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28593	BAO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28593	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28593	HHEAR	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28593	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28593	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28593	NIFSTD	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28593	HINO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_28593	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	FYPO	LOOM
http://purl.obolibrary.org/obo/XCO_0000617	XCO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	DOID	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D011802	RH-MESH	LOOM
http://purl.obolibrary.org/obo/NCIT_C793	BERO	LOOM
http://purl.bioontology.org/ontology/VANDF/4019925	VANDF	LOOM
https://go.drugbank.com/drugs/DB00908	MDM	LOOM
http://purl.bioontology.org/ontology/LNC/LP16271-6	LOINC	LOOM
http://purl.bioontology.org/ontology/CPT/80194	CPT	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039022	PDQ	LOOM
http://purl.obolibrary.org/obo/IDOMAL_0000236	IDOMAL	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.605.687.637	RH-MESH	LOOM
http://purl.obolibrary.org/obo/MESH_D011802	BERO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017900	PMAPP-PMO	LOOM
http://purl.jp/bio/4/id/200906078899627364	IOBC	LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass7b7991cd_f83c_48a4_8a21_f39e927d8858	WWECA	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.810.699	RH-MESH	LOOM
http://www.co-ode.org/ontologies/galen#Quinidine	GALEN	LOOM
http://purl.bioontology.org/ontology/SNMI/C-80460	SNMI	LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Quinidine	STMSO	LOOM
http://purl.bioontology.org/ontology/ATC/C01BA01	ATC	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372697008	SNOMEDCT	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C793	NCIT	LOOM
http://purl.bioontology.org/ontology/RCD/bc9..	RCD	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0034414	OCHV	LOOM
http://purl.obolibrary.org/obo/OMIT_0012736	OMIT	LOOM
http://purl.bioontology.org/ontology/MESH/D011802	MESH	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#10495	OCHV	LOOM
http://purl.bioontology.org/ontology/CSP/2532-7642	CRISP	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148010	NDFRT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.206.636	RH-MESH	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	BAO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	HHEAR	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	NIFSTD	LOOM
http://purl.obolibrary.org/obo/CHEBI_28593	HINO	LOOM
http://www.drugbank.ca/drugs/DB00908	FTC	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU060473	LOINC	LOOM
http://purl.bioontology.org/ontology/RXNORM/9068	RXNORM	LOOM
http://www.gamuts.net/entity#quinidine	GAMUTS	LOOM
http://stirdf.jst.go.jp/id/200907062084930259	IOBC	LOOM
http://www.stanford.edu/~coulet/phare.owl#Quinidine	PHARE	LOOM
http://purl.bioontology.org/ontology/NDDF/000618	NDDF	LOOM
http://www.bioassayontology.org/bao#BAO_0000797	BAO	LOOM