loading...| Preferred Name |
amoxicillin |
|
| Synonyms |
amoxicillinum (2S,5R,6R)-6-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid AMPC amoxicillin Amolin Amopenixin Clamoxyl amoxycillin amoxicilline 6-(p-hydroxy-alpha-aminophenylacetamido)penicillanic acid alpha-amino-p-hydroxybenzylpenicillin Amoxicillin Moxal AX amoxicilina Amoxicillin anhydrous (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylic acid p-hydroxyampicillin C16H19N3O5S |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_2676 |
|
| AHFScode |
08:12.16.08 |
|
| altId |
CHEBI:133770 |
|
| ATCCode |
J01CA04 |
|
| CASRN |
26787-78-0 |
|
| DBBrand |
trimox polymox zimox histocillin amoxiden amolin delacillin ospamox unicillin dispermox ampc clamoxyl cemoxin metafarma capsules amoxil metifarma capsules utimox pamoxicillin lamoxy amoxi amoxi-mast aspenil hiconcil amopen piramox tolodina actimoxi moxal moxacin amoxivet amoxibiotic flemoxin vetramox sumox amopenixin efpenix ibiamox robamox sawamox pm bristamox anemolin wymox biomox amoclen imacillin |
|
| DBname |
amoxicillin |
|
| DBSynonym |
amoxicillin trihydrate amoxicillin anhydrous amoxicilline [inn-french] amoxycillin amoxicillinum [inn-latin] amoxicilina [inn-spanish] amoxycillin trihydrate d-amoxicillin p-hydroxyampicillin |
|
| Definition |
A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-(4-hydroxyphenyl)acetamido group. |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0000411 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000103 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0000498 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0001106 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000487 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000565 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0001366 http://purl.obolibrary.org/obo/OAE_0000480 |
|
| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C16H19N3O5S/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24)/t9-,10-,11+,14-/m1/s1 |
|
| InChIKey |
InChIKey=LSQZJLSUYDQPKJ-NJBDSQKTSA-N |
|
| inhibits |
http://purl.obolibrary.org/obo/dinto_4015 http://purl.obolibrary.org/obo/dinto_4065 |
|
| is metabolised by | ||
| label |
amoxicillin |
|
| may interact with |
http://purl.obolibrary.org/obo/CHEBI_44185 http://purl.obolibrary.org/obo/CHEBI_63334 http://purl.obolibrary.org/obo/CHEBI_50845 http://purl.obolibrary.org/obo/dinto_DB01357 http://purl.obolibrary.org/obo/CHEBI_27701 http://purl.obolibrary.org/obo/CHEBI_6805 http://purl.obolibrary.org/obo/CHEBI_27902 http://purl.obolibrary.org/obo/dinto_DB00977 |
|
| prefixIRI |
obo2:CHEBI_2676 |
|
| prefLabel |
amoxicillin |
|
| SMILES |
[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)C1=CC=C(O)C=C1)C(O)=O [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccc(O)cc1)C(O)=O |
|
| Synonym |
amoxicillinum (2S,5R,6R)-6-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid AMPC amoxicillin Amolin Amopenixin Clamoxyl amoxycillin amoxicilline 6-(p-hydroxy-alpha-aminophenylacetamido)penicillanic acid alpha-amino-p-hydroxybenzylpenicillin Amoxicillin Moxal AX amoxicilina Amoxicillin anhydrous (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylic acid p-hydroxyampicillin C16H19N3O5S |
|
| xref |
KEGG DRUG:D07452 ChEBI:2676 Reaxys:4274654 CiteXplore:12833570 Drugs.com:http://www.drugs.com/amoxicillin.html RxList:http://www.rxlist.com/cgi/generic/amox.htm PharmGKB:PA448406 Patent:DE1942693 CiteXplore:11906332 KEGG COMPOUND:C06827 Patent:US3192198 PubChem Substance:46507578 CiteXplore:16033609 PubChem Compound:33613 ChEMBL:243284 CASRN:26787-78-0 Patent:GB978178 DrugBank:DB01060 CiteXplore:10930630 CiteXplore:12569987 Drugs Product Database (DPD):2262886 National Drug Code Directory:0781-6039-58 CiteXplore:2083978 CiteXplore:11431418 Beilstein:4274654 Wikipedia:Amoxicillin Wikipedia:http://en.wikipedia.org/wiki/Amoxicillin Patent:GB1241844 CiteXplore:12850488 ChemSpider:31006 |
|
| subClassOf |