The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

amitriptyline

Synonyms

dimethyl({3-[(2Z)-tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]propyl})amine

C20H23N

5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene

3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine

10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene

3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine

5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene

Amitriptylin

Amitriptyline

3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine

10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Delta(5),gamma-propylamine

5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptadiene

ID

http://purl.obolibrary.org/obo/CHEBI_2666

activates

http://purl.obolibrary.org/obo/dinto_2042

http://purl.obolibrary.org/obo/dinto_3960

http://purl.obolibrary.org/obo/dinto_0760

http://purl.obolibrary.org/obo/dinto_1246

AHFScode

28:16.04.28

ATCCode

N06AA09

blocks

http://purl.obolibrary.org/obo/dinto_3887

http://purl.obolibrary.org/obo/dinto_1071

http://purl.obolibrary.org/obo/dinto_0234

http://purl.obolibrary.org/obo/dinto_0703

http://purl.obolibrary.org/obo/dinto_0392

http://purl.obolibrary.org/obo/dinto_3475

http://purl.obolibrary.org/obo/dinto_1005

http://purl.obolibrary.org/obo/dinto_2097

http://purl.obolibrary.org/obo/dinto_3182

http://purl.obolibrary.org/obo/dinto_1135

CASRN

50-48-6

DBBrand

saroten

adepress

redomex

flavyl

sylvemid

triptilin

horizon

triptanol

adepril

damilan

amitid

laroxyl

damilen

sarotex

amitril

lantron

lentizol

triptisol

laroxil

tryptizol

elanil

tryptanol

elavil

endep

proheptadiene

seroten

DBname

amitriptyline

DBSalt

amitriptyline hydrochloride

DBSynonym

amitriptylin

amitryptyline

amitriprolidine

amytriptiline

amitryptiline

Definition

A tricyclic antidepressant that has formula C20H23N.

has effect

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0001068

http://purl.obolibrary.org/obo/OAE_0000309

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000608

http://purl.obolibrary.org/obo/OAE_0000589

http://purl.obolibrary.org/obo/OAE_0000642

http://purl.obolibrary.org/obo/OAE_0000842

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0001105

http://purl.obolibrary.org/obo/OAE_0001001

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000920

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000898

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0000268

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000534

http://purl.obolibrary.org/obo/OAE_0001489

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000418

http://purl.obolibrary.org/obo/OAE_0000596

http://purl.obolibrary.org/obo/OAE_0000491

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0000512

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0001515

http://purl.obolibrary.org/obo/OAE_0000365

http://purl.obolibrary.org/obo/OAE_0000785

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000487

http://purl.obolibrary.org/obo/OAE_0000542

http://purl.obolibrary.org/obo/OAE_0000921

http://purl.obolibrary.org/obo/OAE_0000403

http://purl.obolibrary.org/obo/OAE_0000752

http://purl.obolibrary.org/obo/OAE_0001069

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000881

http://purl.obolibrary.org/obo/OAE_0000038

http://purl.obolibrary.org/obo/OAE_0001026

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000660

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0001309

http://purl.obolibrary.org/obo/OAE_0000607

http://purl.obolibrary.org/obo/OAE_0000551

has pharmacological target

http://purl.obolibrary.org/obo/dinto_0068

http://purl.obolibrary.org/obo/dinto_0392

http://purl.obolibrary.org/obo/dinto_2714

has role

http://purl.obolibrary.org/obo/CHEBI_35640

InChI

InChI=1S/C20H23N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3

InChIKey

InChIKey=KRMDCWKBEZIMAB-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_0068

http://purl.obolibrary.org/obo/dinto_2849

http://purl.obolibrary.org/obo/dinto_0058

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_0293

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_0062

http://purl.obolibrary.org/obo/dinto_2714

http://purl.obolibrary.org/obo/dinto_4068

http://purl.obolibrary.org/obo/dinto_1221

is metabolised by

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_0293

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0465

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_1221

is transported by

http://purl.obolibrary.org/obo/dinto_1440

label

amitriptyline

may interact with

http://purl.obolibrary.org/obo/dinto_DB01346

http://purl.obolibrary.org/obo/dinto_DB00427

http://purl.obolibrary.org/obo/CHEBI_6794

http://purl.obolibrary.org/obo/CHEBI_9449

http://purl.obolibrary.org/obo/dinto_DB00237

http://purl.obolibrary.org/obo/dinto_DB00503

http://purl.obolibrary.org/obo/CHEBI_53289

http://purl.obolibrary.org/obo/CHEBI_63620

http://purl.obolibrary.org/obo/CHEBI_195280

http://purl.obolibrary.org/obo/dinto_DB01291

http://purl.obolibrary.org/obo/dinto_DB06704

http://purl.obolibrary.org/obo/CHEBI_5118

http://purl.obolibrary.org/obo/CHEBI_70707

http://purl.obolibrary.org/obo/CHEBI_37924

http://purl.obolibrary.org/obo/CHEBI_9943

http://purl.obolibrary.org/obo/CHEBI_28077

http://purl.obolibrary.org/obo/dinto_DB00196

http://purl.obolibrary.org/obo/dinto_DB00476

http://purl.obolibrary.org/obo/CHEBI_8093

http://purl.obolibrary.org/obo/dinto_DB01341

http://purl.obolibrary.org/obo/CHEBI_32250

http://purl.obolibrary.org/obo/CHEBI_18357

http://purl.obolibrary.org/obo/dinto_DB01026

http://purl.obolibrary.org/obo/CHEBI_9566

http://purl.obolibrary.org/obo/CHEBI_5138

http://purl.obolibrary.org/obo/dinto_DB00752

http://purl.obolibrary.org/obo/dinto_DB00382

http://purl.obolibrary.org/obo/dinto_DB06700

http://purl.obolibrary.org/obo/CHEBI_45716

http://purl.obolibrary.org/obo/dinto_DB01208

http://purl.obolibrary.org/obo/CHEBI_61049

http://purl.obolibrary.org/obo/CHEBI_4670

http://purl.obolibrary.org/obo/dinto_DB00780

http://purl.obolibrary.org/obo/CHEBI_51364

http://purl.obolibrary.org/obo/CHEBI_18243

http://purl.obolibrary.org/obo/CHEBI_5557

http://purl.obolibrary.org/obo/CHEBI_6780

http://purl.obolibrary.org/obo/CHEBI_2549

http://purl.obolibrary.org/obo/CHEBI_9635

http://purl.obolibrary.org/obo/dinto_DB00209

http://purl.obolibrary.org/obo/dinto_DB01364

http://purl.obolibrary.org/obo/dinto_DB00488

http://purl.obolibrary.org/obo/CHEBI_3720

http://purl.obolibrary.org/obo/CHEBI_10124

http://purl.obolibrary.org/obo/CHEBI_149226

http://purl.obolibrary.org/obo/dinto_DB01363

http://purl.obolibrary.org/obo/dinto_DB01171

http://purl.obolibrary.org/obo/CHEBI_3387

http://purl.obolibrary.org/obo/CHEBI_102524

http://purl.obolibrary.org/obo/dinto_DB01366

http://purl.obolibrary.org/obo/dinto_DB01365

http://purl.obolibrary.org/obo/CHEBI_46631

http://purl.obolibrary.org/obo/CHEBI_9654

http://purl.obolibrary.org/obo/dinto_DB00397

http://purl.obolibrary.org/obo/CHEBI_28593

http://purl.obolibrary.org/obo/dinto_DB00726

http://purl.obolibrary.org/obo/dinto_DB01623

http://purl.obolibrary.org/obo/CHEBI_3699

http://purl.obolibrary.org/obo/dinto_DB00342

http://purl.obolibrary.org/obo/dinto_DB00723

http://purl.obolibrary.org/obo/dinto_DB00857

http://purl.obolibrary.org/obo/CHEBI_8874

http://purl.obolibrary.org/obo/dinto_DB00816

http://purl.obolibrary.org/obo/CHEBI_51209

http://purl.obolibrary.org/obo/CHEBI_45367

http://purl.obolibrary.org/obo/dinto_DB00365

http://purl.obolibrary.org/obo/dinto_DB00582

http://purl.obolibrary.org/obo/CHEBI_10119

http://purl.obolibrary.org/obo/CHEBI_28918

http://purl.obolibrary.org/obo/CHEBI_68575

http://purl.obolibrary.org/obo/CHEBI_156095

http://purl.obolibrary.org/obo/CHEBI_42944

http://purl.obolibrary.org/obo/dinto_DB01105

http://purl.obolibrary.org/obo/dinto_DB01064

http://purl.obolibrary.org/obo/dinto_DB01247

http://purl.obolibrary.org/obo/CHEBI_27796

prefixIRI

obo2:CHEBI_2666

prefLabel

amitriptyline

related with

http://purl.obolibrary.org/obo/dinto_3582

http://purl.obolibrary.org/obo/dinto_0217

http://purl.obolibrary.org/obo/dinto_1166

SMILES

CN(C)CCC=C1c2ccccc2CCc2ccccc12

CN(C)CCC=C1C2=CC=CC=C2CCC2=CC=CC=C12

Synonym

dimethyl({3-[(2Z)-tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]propyl})amine

C20H23N

5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene

3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine

10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene

3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine

5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene

Amitriptylin

Amitriptyline

3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine

10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Delta(5),gamma-propylamine

5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptadiene

xref

ChEBI:2666

Wikipedia:Amitriptyline

Drugs Product Database (DPD):654515

PharmGKB:PA448385

National Drug Code Directory:53489-104-07

RxList:http://www.rxlist.com/cgi/generic/amitrip.htm

NIST Chemistry WebBook:50-48-6

CASRN:50-48-6

Drugs.com:http://www.drugs.com/amitriptyline.html

ChEMBL:127072

Wikipedia:http://en.wikipedia.org/wiki/Amitriptyline

PubChem Compound:2160

ChemSpider:2075

DrugBank:DB00321

PubChem Substance:46508798

KEGG COMPOUND:C06824

Beilstein:2217885

IUPHAR:200

Guide To Pharmacology:200

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Delete Mapping To Ontology Source
http://scai.fraunhofer.de/MSOntology#Amitriptyline MSO LOOM
http://purl.bioontology.org/ontology/CSP/0780-6741 CRISP LOOM
http://purl.jp/bio/4/id/200906000783681540 IOBC LOOM
http://www.case.edu/EpSO.owl#Amitriptyline EPSO LOOM
http://purl.bioontology.org/ontology/NDDF/004600 NDDF LOOM
http://scdontology.h3abionet.org/ontology/SCDO_0004190 SCDO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62005 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62005 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62005 NCIT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004907 LOINC LOOM
http://purl.obolibrary.org/obo/CHEBI_2666 ODNAE LOOM
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http://purl.bioontology.org/ontology/RCD/x01Aw RCD LOOM
http://purl.bioontology.org/ontology/RXNORM/704 RXNORM LOOM
http://purl.bioontology.org/ontology/UATC/N06AA09 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.181.384.100 RH-MESH LOOM
http://www.limics.fr/ontologies/ontoparonmed#Laroxyl ONTOPARON LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Amitriptyline APAONTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.847.181.384.100 RH-MESH LOOM
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http://scai.fraunhofer.de/AlzheimerOntology#amitriptyline ADO LOOM
http://www.co-ode.org/ontologies/galen#Amitriptyline GALEN LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0002600 OCHV LOOM
http://purl.bioontology.org/ontology/LNC/LP14983-8 LOINC LOOM
http://www.gamuts.net/entity#amitriptyline GAMUTS LOOM
http://purl.bioontology.org/ontology/VANDF/4019607 VANDF LOOM
http://bmi.utah.edu/ontologies/peontology/C0002600 RAO LOOM
http://purl.bioontology.org/ontology/SNMI/C-62250 SNMI LOOM