The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

insulin, isophane
Synonyms
ID

http://purl.obolibrary.org/obo/dinto_DB08914

activates

http://purl.obolibrary.org/obo/dinto_0892

ATCCode

A10AB01

binds

http://purl.obolibrary.org/obo/dinto_0892

CASRN

53027-39-7

DBBrand

novolin? ge nph

humulin n pen

novolin n relion

novolin n

humulin n

humulin? n

DBSynonym

isophane insulin

nph insulin

Definition

Isophane insulin or NPH insulin (neutral protamine Hagedorn) is an intermediate-acting insulin to improve glycemic control. It is synthesized using a strain of Escherichia coli bacteria that has been genetically altered to produce human insulin. Human insulin isophane suspension consists of a crystalline suspension of human insulin with protamine and zinc. This combination results in an intermediate-acting insulin with a slower onset of action and longer duration of activity than regular human insulin.

has pharmacological target

http://purl.obolibrary.org/obo/dinto_0892

label

insulin, isophane

modulates

http://purl.obolibrary.org/obo/dinto_0892

prefixIRI

obo2:dinto_DB08914

prefLabel

insulin, isophane

xref

Wikipedia:http://en.wikipedia.org/wiki/NPH_insulin

RxList:http://www.rxlist.com/novolin-n-innolet-drug.htm

Drugs.com:http://www.drugs.com/mtm/insulin-isophane.html

National Drug Code Directory:0002-8315-01

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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