loading...| Preferred Name | certolizumab pegol | |
| Synonyms |
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| ID |
http://purl.obolibrary.org/obo/dinto_DB08904 |
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| AHFScode |
56:92 |
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| ATCCode |
L04AB05 |
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| binds | ||
| CASRN |
428863-50-7 |
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| DBBrand |
cimzia |
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| DBSynonym |
cdp870 |
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| Definition |
Certolizumab pegol is a recombinant Fab antibody fragment against tumor necrosis factor alpha which is conjugated to an approximately 40kDa polyethylene glycol (PEG2MAL40K). Polyethylene glycol helps to delay the metabolism and elimination of the drugs. Chemically, the light chain is made up of 214 amino acid residues while the heavy chain is composed of 229 amino acid residues. The molecular mass of the Fab antibody fragment itself is 47.8 kDa. It is used for the treatment of rheumatoid arthritis and Crohn?s disease. FDA approved on April 22, 2008 |
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| has pharmacological target | ||
| label |
certolizumab pegol |
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| may interact with |
http://purl.obolibrary.org/obo/dinto_DB00108 http://purl.obolibrary.org/obo/dinto_DB06674 http://purl.obolibrary.org/obo/dinto_DB00073 |
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| prefixIRI |
obo2:dinto_DB08904 |
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| prefLabel |
certolizumab pegol |
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| related with | ||
| xref |
Drugs.com:http://www.drugs.com/ppa/certolizumab-pegol.html Wikipedia:http://en.wikipedia.org/wiki/Certolizumab_pegol RxList:http://www.rxlist.com/cimzia-drug.htm National Drug Code Directory:50474-710-79 PharmGKB:PA165107055 |
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| subClassOf |