The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Id http://purl.obolibrary.org/obo/dinto_DB08864
http://purl.obolibrary.org/obo/dinto_DB08864
Preferred Name

rilpivirine
Synonyms
C22H18N6
4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile
Type http://www.w3.org/2002/07/owl#Class

All Properties

label
rilpivirine
prefLabel
rilpivirine
is metabolised by
Definition
Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine, a class of molecules that resemble pyrimidine nucleotides found in DNA. Because of its flexible chemical structure, resistance of rilpivirine is less likely to develop than other NNRTI s. FDA approved on May 20, 2011.
DBBrand
edurant
ATCCode
J05AG05
modulates
SMILES
CC1=CC(\C=C\C#N)=CC(C)=C1NC1=CC=NC(NC2=CC=C(C=C2)C#N)=N1
InChI
InChI=1/C22H18N6/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17(14-24)6-8-19/h3-9,11-13H,1-2H3,(H2,25,26,27,28)/b4-3+
CASRN
500287-72-9
prefixIRI
obo2:dinto_DB08864
Synonym
C22H18N6
4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile
binds
InChIKey
InChIKey=YIBOMRUWOWDFLG-ONEGZZNKNA-N
subClassOf
may interact with
inhibits
induces
is substrate of
type
xref
Wikipedia:http://en.wikipedia.org/wiki/Rilpivirine
Drugs.com:http://www.drugs.com/cdi/rilpivirine.html
RxList:http://www.rxlist.com/edurant-drug.htm
National Drug Code Directory:59676-278-01
ChEBI:68606
DBSynonym
tmc278
activates
AHFScode
8:18.08.16
DBSalt
rilpivirine hydrochlorie
has pharmacological target
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