The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Id http://purl.obolibrary.org/obo/dinto_DB08838
http://purl.obolibrary.org/obo/dinto_DB08838
Preferred Name

agmatine
Synonyms
1-(4-aminobutyl)guanidine
C5H14N4
Type http://www.w3.org/2002/07/owl#Class

All Properties

prefLabel
agmatine
label
agmatine
DBSynonym
(4-aminobutyl) guanidine
Definition
Agmantine is a natural metabolite of the amino acid arginine. It is formed when arginine is decarboxylated by the enzyme arginine decarboxylase and is found naturally in ragweed pollen, ergot fungi, octopus muscle, herring sperm, sponges, and the mammalian brain. Agmatine is both an experimental and investigational drug. As an investigational drug, it is being studied in a non-blinded prospective case study in the United States looking at patients who have been diagnosed with small fiber peripheral neuropathy between the ages of 18 to 75 years. Up to now (July 2013), the results of this study have not yet been published. As an experimental drug, agmatine is being studied for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma, and neuropathic pain), and psychiatric conditions (depression, anxiety, schizophrenia, and cognition). The exact mechanism of action is still being investigated for all of the potential indications of agmatine.
DBSalt
agmatine sulphate
has pharmacological target
activates
type
InChIKey
InChIKey=QYPPJABKJHAVHS-UHFFFAOYSA-N
blocks
Synonym
1-(4-aminobutyl)guanidine
C5H14N4
xref
Wikipedia:http://en.wikipedia.org/wiki/Agmatine
ChEBI:17431
CASRN
306-60-5
prefixIRI
obo2:dinto_DB08838
is transported by
SMILES
NCCCCNC(N)=N
InChI
InChI=1S/C5H14N4/c6-3-1-2-4-9-5(7)8/h1-4,6H2,(H4,7,8,9)
subClassOf
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