The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Id http://purl.obolibrary.org/obo/dinto_DB08837
http://purl.obolibrary.org/obo/dinto_DB08837
Preferred Name

tetraethylammonium
Synonyms
tetraethylazanium
C8H20N
Type http://www.w3.org/2002/07/owl#Class

All Properties

prefLabel
tetraethylammonium
label
tetraethylammonium
DBSynonym
tea
Definition
Tetraethylammonium is an experimental drug with no approved indication or marketed formulation. The only marketed drug containing tetraethylammonium was a combination drug called Fosglutamina B6, but this drug has now been discontinued. As an experimental agent, tetraethylammonium is used in its salt forms such as tetraethylammonium chloride and tetraethylammonium bromide. Its mechanism of action is still being investigated, but it is known that tetraethylammonium blocks autonomic ganglia, calcium- and voltage- activated potassium channels, and nicotinic acetylcholine receptors. Because of its inhibitory actions at the autonomic ganglia, tetraethylammonium was thought to be a potential therapeutic vasodilator but serious toxic effects were found. The most common use of tetraethylammonium presently is as a pharmacological research agent that blocks selective potassium channels. Structurally, tetraethylammonium is positively charged due to its central quaternary ammonium.
DBSalt
tetraethylammonium chloride
tetraethylammonium phosphate
tetraethylammonium chloride hydrate
tetraethylammonium hydroxide
tetraethylammonium iodide
tetraethylammonium bromide
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activates
inhibits
type
InChIKey
InChIKey=CBXCPBUEXACCNR-UHFFFAOYSA-N
Synonym
tetraethylazanium
C8H20N
xref
ChEBI:44296
Wikipedia:http://en.wikipedia.org/wiki/Tetraethylammonium
CASRN
66-40-0
prefixIRI
obo2:dinto_DB08837
related with
SMILES
CC[N+](CC)(CC)CC
InChI
InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
subClassOf
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