The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

hyaluronan
Synonyms
ID

http://purl.obolibrary.org/obo/dinto_DB08818

ATCCode

D03AX05

R01AX09

S01KA01

M09AX01

binds

http://purl.obolibrary.org/obo/dinto_4192

http://purl.obolibrary.org/obo/dinto_1689

http://purl.obolibrary.org/obo/dinto_0787

CASRN

9067-32-7

DBBrand

monovisc

legend

amvisic plus

hyalart

viscure

amo vitrax

synvisc

hyalgan

gonilert

hylo-comod

yardel

recosyn

cystistar

euflexxa

DBSynonym

hyaluronate

hyaluronic acid

hyaluronic acid sodium salt

sodium hyaluronate

Definition

Sodium hyaluronate is the sodium salt of hyaluronan. The term hyaluronate also refers to the conjugate base of hyaluronic acid. Because the molecule typically exists in vivo in its polyanionic form, it is most commonly referred to as hyaluronan. It is a visco-elastic polymer normally found in the aqueous and vitreous humour. Sodium hyaluronate is a viscous solution consisting of a high molecular weight (500,000-730,000 daltons) fraction of purified natural sodium hyaluronate in buffered physiological sodium chloride. Hyaluronic acid is a natural complex sugar of the glycosaminoglycan family and is a long-chain polymer containing repeating disaccharide units of Na-glucuronate-N-acetylglucosamine. Sodium hyaluronate occurs naturally on the corneal endothelium, bound to specific receptors for which it has a high affinity.

has pharmacological target

http://purl.obolibrary.org/obo/dinto_4192

http://purl.obolibrary.org/obo/dinto_1689

http://purl.obolibrary.org/obo/dinto_0787

label

hyaluronan

prefixIRI

obo2:dinto_DB08818

prefLabel

hyaluronan

related with

http://purl.obolibrary.org/obo/dinto_4192

http://purl.obolibrary.org/obo/dinto_1689

http://purl.obolibrary.org/obo/dinto_0787

xref

Wikipedia:http://en.wikipedia.org/wiki/Sodium_hyaluronate

PharmGKB:PA165958431

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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