Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB06751
http://purl.obolibrary.org/obo/dinto_DB06751
|
|---|---|
| Preferred Name | drotaverine |
| Synonyms |
C24H31NO4
(1Z)-1-[(3,4-diethoxyphenyl)methylidene]-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | drotaverine
|
|---|---|
| label | drotaverine
|
| DBSynonym | drotaverin
|
| ATCCode | A03AD02
|
| Definition | Drotaverine (INN, also known as drotaverin) is an antispasmodic drug, structurally related to papaverine. Drotaverine is a selective inhibitor of phosphodiesterase 4, and has no anticholinergic effects. Drotaverine has been shown to possess dose-dependant analgesic effects in animal models. One small study has shown drotaverine to be eliminated mainly non-renally.
|
| has pharmacological target | |
| inhibits | |
| type | |
| InChIKey | InChIKey=OMFNSKIUKYOYRG-MOSHPQCFSA-N
|
| Synonym |
C24H31NO4
(1Z)-1-[(3,4-diethoxyphenyl)methylidene]-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline
|
| xref |
PharmGKB:PA165958398
Wikipedia:http://en.wikipedia.org/wiki/Drotaverine
ChemSpider:1361582
PubChem Compound:1712095
PubChem Substance:99443287
|
| CASRN | 985-12-6
|
| prefixIRI | obo2:dinto_DB06751
|
| SMILES | CCOC1=C(OCC)C=C(\C=C2/NCCC3=CC(OCC)=C(OCC)C=C23)C=C1
|
| InChI | InChI=1S/C24H31NO4/c1-5-26-21-10-9-17(14-22(21)27-6-2)13-20-19-16-24(29-8-4)23(28-7-3)15-18(19)11-12-25-20/h9-10,13-16,25H,5-8,11-12H2,1-4H3/b20-13-
|
| DBBrand |
drotin
no-spa
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |