The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

sparteine
Synonyms

C15H26N2

(1S,2S,9S,10S)-7,15-diazatetracyclo[7.7.1.0^{2,7}.0^{10,15}]heptadecane
ID

http://purl.obolibrary.org/obo/dinto_DB06727
ATCCode

C01BA04
binds

http://purl.obolibrary.org/obo/dinto_2993
CASRN

90-39-1
DBSynonym

sparteinum sulfuricum

pachycarpine

genisteine

esparteina

lupinidine

d-sparteine

sparteinum

(-)-sparteine
Definition

Sparteine is a class 1a antiarrhythmic agent; a sodium channel blocker. It is an alkaloid and can be extracted from scotch broom. It is the predominant alkaloid in Lupinus mutabilis, and is thought to chelate the bivalents calcium and magnesium. It is not FDA approved for human use as an antiarrhythmic agent, and it is not included in the Vaughn Williams classification of antiarrhythmic drugs.
InChI

InChI=1S/C15H26N2/c1-3-7-16-11-13-9-12(14(16)5-1)10-17-8-4-2-6-15(13)17/h12-15H,1-11H2/t12-,13-,14-,15-/m0/s1
InChIKey

InChIKey=SLRCCWJSBJZJBV-AJNGGQMLSA-N
inhibits

http://purl.obolibrary.org/obo/dinto_2993
is metabolised by

http://purl.obolibrary.org/obo/dinto_2993
is substrate of

http://purl.obolibrary.org/obo/dinto_2993
label

sparteine
prefixIRI

obo2:dinto_DB06727
prefLabel

sparteine
SMILES

C1CCN2C[C@@H]3C[C@@H](CN4CCCC[C@@H]34)[C@@H]2C1
Synonym

C15H26N2

(1S,2S,9S,10S)-7,15-diazatetracyclo[7.7.1.0^{2,7}.0^{10,15}]heptadecane
xref

ChemSpider:147139

PharmGKB:PA452610

PubChem Compound:46937024

Drugs Product Database (DPD):1970631

PubChem Substance:99443273

Wikipedia:http://en.wikipedia.org/wiki/Sparteine

ChEBI:28827
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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