The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Preferred Name	dalfampridine
Synonyms	C5H6N2 pyridin-4-amine
ID	http://purl.obolibrary.org/obo/dinto_DB06637
AHFScode	92:92
ATCCode	N07XX07
binds	http://purl.obolibrary.org/obo/dinto_2650 http://purl.obolibrary.org/obo/dinto_0058 http://purl.obolibrary.org/obo/dinto_2849 http://purl.obolibrary.org/obo/dinto_1741 http://purl.obolibrary.org/obo/dinto_1740 http://purl.obolibrary.org/obo/dinto_1748 http://purl.obolibrary.org/obo/dinto_1747 http://purl.obolibrary.org/obo/dinto_1735 http://purl.obolibrary.org/obo/dinto_1731 http://purl.obolibrary.org/obo/dinto_1733 http://purl.obolibrary.org/obo/dinto_1739 http://purl.obolibrary.org/obo/dinto_1736 http://purl.obolibrary.org/obo/dinto_1738 http://purl.obolibrary.org/obo/dinto_0062 http://purl.obolibrary.org/obo/dinto_1751 http://purl.obolibrary.org/obo/dinto_1750 http://purl.obolibrary.org/obo/dinto_0293
blocks	http://purl.obolibrary.org/obo/dinto_2650 http://purl.obolibrary.org/obo/dinto_0058 http://purl.obolibrary.org/obo/dinto_2849 http://purl.obolibrary.org/obo/dinto_1741 http://purl.obolibrary.org/obo/dinto_1740 http://purl.obolibrary.org/obo/dinto_1748 http://purl.obolibrary.org/obo/dinto_1747 http://purl.obolibrary.org/obo/dinto_1735 http://purl.obolibrary.org/obo/dinto_1731 http://purl.obolibrary.org/obo/dinto_1733 http://purl.obolibrary.org/obo/dinto_1739 http://purl.obolibrary.org/obo/dinto_1736 http://purl.obolibrary.org/obo/dinto_1738 http://purl.obolibrary.org/obo/dinto_0062 http://purl.obolibrary.org/obo/dinto_1751 http://purl.obolibrary.org/obo/dinto_1750
CASRN	504-24-5
DBBrand	ampyra fampyra
DBSynonym	fampridine-sr el-970 4-aminopyridine 4-ap fampridine
Definition	Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients. FDA approved on January 22, 2010.
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2650 http://purl.obolibrary.org/obo/dinto_0058 http://purl.obolibrary.org/obo/dinto_2849 http://purl.obolibrary.org/obo/dinto_1741 http://purl.obolibrary.org/obo/dinto_1740 http://purl.obolibrary.org/obo/dinto_1748 http://purl.obolibrary.org/obo/dinto_1747 http://purl.obolibrary.org/obo/dinto_1735 http://purl.obolibrary.org/obo/dinto_1731 http://purl.obolibrary.org/obo/dinto_1733 http://purl.obolibrary.org/obo/dinto_1739 http://purl.obolibrary.org/obo/dinto_1736 http://purl.obolibrary.org/obo/dinto_1738 http://purl.obolibrary.org/obo/dinto_0062 http://purl.obolibrary.org/obo/dinto_1751 http://purl.obolibrary.org/obo/dinto_1750
InChI	InChI=1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
InChIKey	InChIKey=NUKYPUAOHBNCPY-UHFFFAOYSA-N
is metabolised by	http://purl.obolibrary.org/obo/dinto_0293
is substrate of	http://purl.obolibrary.org/obo/dinto_0293
label	dalfampridine
modulates	http://purl.obolibrary.org/obo/dinto_2650 http://purl.obolibrary.org/obo/dinto_0058 http://purl.obolibrary.org/obo/dinto_2849 http://purl.obolibrary.org/obo/dinto_1741 http://purl.obolibrary.org/obo/dinto_1740 http://purl.obolibrary.org/obo/dinto_1748 http://purl.obolibrary.org/obo/dinto_1747 http://purl.obolibrary.org/obo/dinto_1735 http://purl.obolibrary.org/obo/dinto_1731 http://purl.obolibrary.org/obo/dinto_1733 http://purl.obolibrary.org/obo/dinto_1739 http://purl.obolibrary.org/obo/dinto_1736 http://purl.obolibrary.org/obo/dinto_1738 http://purl.obolibrary.org/obo/dinto_0062 http://purl.obolibrary.org/obo/dinto_1751 http://purl.obolibrary.org/obo/dinto_1750
prefixIRI	obo2:dinto_DB06637
prefLabel	dalfampridine
SMILES	NC1=CC=NC=C1
Synonym	C5H6N2 pyridin-4-amine
xref	ChEBI:34385 RxList:http://www.rxlist.com/ampyra-drug.htm Drugs.com:http://www.drugs.com/ampyra.html National Drug Code Directory:10144-427-60 Wikipedia:http://en.wikipedia.org/wiki/4-Aminopyridine
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/NCIT_C76777	BERO	LOOM
http://purl.obolibrary.org/obo/DRON_00019616	PDRO	LOOM
http://www.drugbank.ca/drugs/DB06637	FTC	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C76777	NCIT	LOOM
http://purl.bioontology.org/ontology/VANDF/4029704	VANDF	LOOM
http://scai.fraunhofer.de/MSOntology#Dalfampridine	MSO	LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Dalfampridine	STMSO	LOOM
http://purl.bioontology.org/ontology/NDDF/006829	NDDF	LOOM
http://purl.bioontology.org/ontology/RXNORM/897018	RXNORM	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/80994002	SNOMEDCT	LOOM
https://go.drugbank.com/drugs/DB06637	MDM	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000180628	NDFRT	LOOM