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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB06212
http://purl.obolibrary.org/obo/dinto_DB06212
|
|---|---|
| Preferred Name | tolvaptan |
| Synonyms |
C26H25ClN2O3
N-(4-{[(5R)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | tolvaptan
|
|---|---|
| label | tolvaptan
|
| DBSynonym | opc-41061
|
| ATCCode | C03XA01
|
| Definition | Tolvaptan is used to treat low blood sodium levels (hyponatremia) associated with various conditions like congestive heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormones (SIADH). FDA approved on May 19, 2009.
|
| has effect |
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| has pharmacological target | |
| inhibits | |
| type | |
| InChIKey | InChIKey=GYHCTFXIZSNGJT-XMMPIXPASA-N
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| is metabolised by | |
| blocks | |
| AHFScode | 40:28.28
|
| Synonym | C26H25ClN2O3
N-(4-{[(5R)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide
|
| xref |
PubChem Compound:443894
PubChem Substance:7848276
RxList:http://www.rxlist.com/samsca-drug.htm
Wikipedia:http://en.wikipedia.org/wiki/Tolvaptan
ChemSpider:391976
Drugs.com:http://www.drugs.com/monograph/tolvaptan.html
National Drug Code Directory:59148-021-50
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| CASRN | 150683-30-0
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| prefixIRI | obo2:dinto_DB06212
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| is transported by | |
| SMILES | CC1=CC=CC=C1C(=O)NC1=CC(C)=C(C=C1)C(=O)N1CCC[C@@H](O)C2=C1C=CC(Cl)=C2
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| may interact with |
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| InChI | InChI=1S/C26H25ClN2O3/c1-16-6-3-4-7-20(16)25(31)28-19-10-11-21(17(2)14-19)26(32)29-13-5-8-24(30)22-15-18(27)9-12-23(22)29/h3-4,6-7,9-12,14-15,24,30H,5,8,13H2,1-2H3,(H,28,31)/t24-/m1/s1
|
| DBBrand | samsca
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |