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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB06210
http://purl.obolibrary.org/obo/dinto_DB06210
|
|---|---|
| Preferred Name | eltrombopag |
| Synonyms |
C25H22N4O4
3-(3-{2-[(4Z)-1-(3,4-dimethylphenyl)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-ylidene]hydrazin-1-yl}-2-hydroxyphenyl)benzoic acid
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | eltrombopag
|
|---|---|
| label | eltrombopag
|
| DBSynonym | eltrombopagum
3'-{(2z)-2-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4h-pyrazol-4-ylidene]hydrazino}-2'-hydroxy-3-biphenylcarboxylic acid
sb 497115
|
| ATCCode | B02BX05
|
| Definition | Eltrombopag is used to treat low blood platelet counts in adults with chronic immune (idiopathic) thrombocytopenia (ITP), when certain other medicines, or surgery to remove the spleen, have not worked well enough. ITP is a condition that may cause unusual bruising or bleeding due to an abnormally low number of platelets in the blood. Eltrombopag has also been recently approved (late 2012) for the treatment of thrombocytopenia (low blood platelet counts) in patients with chronic hepatitis C to allow them to initiate and maintain interferon-based therapy.
|
| DBSalt | eltrombopag olamine
|
| activates | |
| inhibits | |
| type | |
| InChIKey | InChIKey=XDXWLKQMMKQXPV-QYQHSDTDSA-N
|
| is metabolised by | |
| AHFScode | 20:16
|
| Synonym | C25H22N4O4
3-(3-{2-[(4Z)-1-(3,4-dimethylphenyl)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-ylidene]hydrazin-1-yl}-2-hydroxyphenyl)benzoic acid
|
| xref |
RxList:http://www.rxlist.com/promacta-drug.htm
Drugs.com:http://www.drugs.com/ppa/eltrombopag.html
Wikipedia:http://en.wikipedia.org/wiki/Eltrombopag
National Drug Code Directory:0007-4640-13
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| CASRN | 496775-61-2
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| prefixIRI | obo2:dinto_DB06210
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| SMILES | CC1=NN(C(=O)\C1=N/NC1=C(O)C(=CC=C1)C1=CC=CC(=C1)C(O)=O)C1=CC=C(C)C(C)=C1
|
| may interact with |
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| InChI | InChI=1S/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,26,30H,1-3H3,(H,32,33)/b27-22-
|
| DBBrand |
promacta
revolade
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| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |