The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Id http://purl.obolibrary.org/obo/dinto_DB04841
http://purl.obolibrary.org/obo/dinto_DB04841
Preferred Name

flunarizine
Synonyms
C26H26F2N2
1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine
Type http://www.w3.org/2002/07/owl#Class

All Properties

label
flunarizine
prefLabel
flunarizine
is metabolised by
blocks
Definition
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
DBBrand
fluvert
apo-flunarizine capsules
vertix
zinasen
flufenal
issium
sibelium
novo-flunarizine
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ATCCode
N07CA03
modulates
SMILES
FC1=CC=C(C=C1)C(N1CCN(C\C=C\C2=CC=CC=C2)CC1)C1=CC=C(F)C=C1
InChI
InChI=1S/C26H26F2N2/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21/h1-15,26H,16-20H2/b7-4+
CASRN
52468-60-7
prefixIRI
obo2:dinto_DB04841
Synonym
C26H26F2N2
1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine
binds
InChIKey
InChIKey=SMANXXCATUTDDT-QPJJXVBHSA-N
subClassOf
may interact with
inhibits
related with
is substrate of
type
xref
Wikipedia:http://en.wikipedia.org/wiki/Flunarizine
PharmGKB:PA164776636
ChemSpider:819216
Drugs Product Database (DPD):846341
BindingDB:50017702
PubChem Substance:46507129
PubChem Compound:941361
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DBSynonym
1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine
flunarizine dihydrochloride
flunarizina [inn-spanish]
flunarizine hydrochloride
flunarizinum [inn-latin]
(e)-1-[bis-(p-fluorophenyl)methyl]-4-cinnamylpiperazine
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has pharmacological target
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