The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Id http://purl.obolibrary.org/obo/dinto_DB04841
http://purl.obolibrary.org/obo/dinto_DB04841
Preferred Name

flunarizine
Synonyms
C26H26F2N2
1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine
Type http://www.w3.org/2002/07/owl#Class

All Properties

prefLabel
flunarizine
label
flunarizine
DBSynonym
1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine
flunarizine dihydrochloride
flunarizina [inn-spanish]
flunarizine hydrochloride
flunarizinum [inn-latin]
(e)-1-[bis-(p-fluorophenyl)methyl]-4-cinnamylpiperazine
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ATCCode
N07CA03
Definition
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
has pharmacological target
inhibits
type
InChIKey
InChIKey=SMANXXCATUTDDT-QPJJXVBHSA-N
is metabolised by
blocks
Synonym
C26H26F2N2
1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine
xref
Wikipedia:http://en.wikipedia.org/wiki/Flunarizine
PharmGKB:PA164776636
ChemSpider:819216
Drugs Product Database (DPD):846341
BindingDB:50017702
PubChem Substance:46507129
PubChem Compound:941361
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CASRN
52468-60-7
prefixIRI
obo2:dinto_DB04841
related with
SMILES
FC1=CC=C(C=C1)C(N1CCN(C\C=C\C2=CC=CC=C2)CC1)C1=CC=C(F)C=C1
may interact with
InChI
InChI=1S/C26H26F2N2/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21/h1-15,26H,16-20H2/b7-4+
DBBrand
fluvert
apo-flunarizine capsules
vertix
zinasen
flufenal
issium
sibelium
novo-flunarizine
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subClassOf
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