The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Id http://purl.obolibrary.org/obo/dinto_DB03496
http://purl.obolibrary.org/obo/dinto_DB03496
Preferred Name

flavopiridol
Synonyms
2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one
C21H20ClNO5
Type http://www.w3.org/2002/07/owl#Class

All Properties

prefLabel
flavopiridol
label
flavopiridol
DBSynonym
hmr-1275
flavo
cpb
alvocidib
flavopiridol hydrochloride
Definition
Flavopiridol is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment of cancer. It works by inhibiting cyclin-dependent kinases, arresting cell division and causing apoptosis in non-small lung cancer cells.
inhibits
type
InChIKey
InChIKey=BIIVYFLTOXDAOV-YVEFUNNKSA-N
Synonym
2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one
C21H20ClNO5
xref
PubChem Substance:46507266
BindingDB:5655
PubChem Compound:5287969
PharmGKB:PA452627
PDB:CPB
CASRN
131740-09-5
prefixIRI
obo2:dinto_DB03496
is transported by
related with
SMILES
CN1CC[C@@H]([C@H](O)C1)C1=C(O)C=C(O)C2=C1OC(=CC2=O)C1=CC=CC=C1Cl
InChI
InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12-,17+/m0/s1
subClassOf
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