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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB01601
http://purl.obolibrary.org/obo/dinto_DB01601
|
|---|---|
| Preferred Name | lopinavir |
| Synonyms |
C37H48N4O5
(2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | lopinavir
|
|---|---|
| label | lopinavir
|
| DBSynonym |
lpv
abt-378
|
| ATCCode | J05AR10
|
| Definition | Lopinavir (ABT-378) is an antiretroviral of the protease inhibitor class. It is marketed by Abbott as Kaletra, a co-formulation with a sub-therapeutic dose of ritonavir, as a component of combination therapy to treat HIV/AIDS.
|
| has pharmacological target | |
| induces | |
| inhibits |
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| type | |
| InChIKey | InChIKey=KJHKTHWMRKYKJE-SUGCFTRWSA-N
|
| is metabolised by | |
| Synonym | C37H48N4O5
(2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
|
| xref |
Wikipedia:http://en.wikipedia.org/wiki/Lopinavir
PubChem Substance:46508588
ChemSpider:83706
PubChem Compound:92727
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/kal1581.shtml
PharmGKB:PA450264
PDB:AB1
BindingDB:578
Drugs Product Database (DPD):2243643
RxList:http://www.rxlist.com/cgi/generic/kaletracaps.htm
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|
| CASRN | 192725-17-0
|
| prefixIRI | obo2:dinto_DB01601
|
| SMILES | CC(C)[C@H](N1CCCNC1=O)C(=O)N[C@H](C[C@H](O)[C@H](CC1=CC=CC=C1)NC(=O)COC1=C(C)C=CC=C1C)CC1=CC=CC=C1
|
| may interact with |
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| InChI | InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1
|
| DBBrand |
aluviran
koletra
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |