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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB01409
http://purl.obolibrary.org/obo/dinto_DB01409
|
|---|---|
| Preferred Name | tiotropium |
| Synonyms |
C19H22NO4S2
(1R,2S,4R,5S)-7-{[2-hydroxy-2,2-bis(thiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.0^{2,4}]nonan-9-ium
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | tiotropium
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|---|---|
| label | tiotropium
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| DBSynonym | tiotropium bromide
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| ATCCode | R03BB04
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| Definition | Tiotropium is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Tiotropium is a muscarinic receptor antagonist, on topical application it acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation, thus producing a bronchodilatory effect.
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| has effect |
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| has pharmacological target | |
| type | |
| InChIKey | InChIKey=LERNTVKEWCAPOY-KYQOMENCSA-N
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| is metabolised by | |
| blocks | |
| AHFScode | 12:08.08
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| Synonym | C19H22NO4S2
(1R,2S,4R,5S)-7-{[2-hydroxy-2,2-bis(thiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.0^{2,4}]nonan-9-ium
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| xref |
RxList:http://www.rxlist.com/cgi/generic/spiriva.htm
PharmGKB:PA164769056
Wikipedia:http://en.wikipedia.org/wiki/Tiotropium
Drugs.com:http://www.drugs.com/cdi/tiotropium.html
PubChem Substance:46504448
Drugs Product Database (DPD):2246793
PubChem Compound:3086654
National Drug Code Directory:0597-0075-75
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| CASRN | 186691-13-4
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| prefixIRI | obo2:dinto_DB01409
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| is transported by | |
| SMILES | C[N+]1(C)[C@H]2CC(C[C@@H]1[C@@H]1O[C@H]21)OC(=O)C(O)(C1=CC=CS1)C1=CC=CS1
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| may interact with |
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| InChI | InChI=1S/C19H22NO4S2/c1-20(2)12-9-11(10-13(20)17-16(12)24-17)23-18(21)19(22,14-5-3-7-25-14)15-6-4-8-26-15/h3-8,11-13,16-17,22H,9-10H2,1-2H3/q+1/t11?,12-,13+,16+,17-
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| DBBrand | spiriva
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| subClassOf |
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| No notes to display |