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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB01384
http://purl.obolibrary.org/obo/dinto_DB01384
|
|---|---|
| Preferred Name | paramethasone |
| Synonyms |
(1S,2R,8S,10S,11S,13R,14R,15S,17S)-8-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
C22H29FO5
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | paramethasone
|
|---|---|
| label | paramethasone
|
| ATCCode | H02AB05
|
| Definition | A glucocorticoid with the general properties of corticosteroids. It has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary fludrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p737)
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| has pharmacological target | |
| activates | |
| inhibits | |
| type | |
| binds | |
| InChIKey | InChIKey=MKPDWECBUAZOHP-AFYJWTTESA-N
|
| is metabolised by | |
| Synonym | (1S,2R,8S,10S,11S,13R,14R,15S,17S)-8-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
C22H29FO5
|
| xref |
PharmGKB:PA164777035
ChemSpider:5664
PubChem Compound:5875
Wikipedia:http://en.wikipedia.org/wiki/Paramethasone
PubChem Substance:46504651
|
| CASRN | 53-33-8
|
| prefixIRI | obo2:dinto_DB01384
|
| SMILES | [H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])C[C@]([H])(F)C2=CC(=O)C=C[C@]12C
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| may interact with |
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| InChI | InChI=1S/C22H29FO5/c1-11-6-14-13-8-16(23)15-7-12(25)4-5-20(15,2)19(13)17(26)9-21(14,3)22(11,28)18(27)10-24/h4-5,7,11,13-14,16-17,19,24,26,28H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19-,20+,21+,22+/m1/s1
|
| DBBrand | haldrone
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |