The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Id http://purl.obolibrary.org/obo/dinto_DB01380
http://purl.obolibrary.org/obo/dinto_DB01380
Preferred Name

cortisone acetate
Synonyms
C23H30O6
2-[(1S,2R,10S,11S,14R,15S)-14-hydroxy-2,15-dimethyl-5,17-dioxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-14-yl]-2-oxoethyl acetate
Type http://www.w3.org/2002/07/owl#Class

All Properties

prefLabel
cortisone acetate
label
cortisone acetate
Definition
Cortisone acetate is a steroid hormone that has both glucocoriticoid and mineral corticoid activities. Corticosteroids are used to provide relief for inflamed areas of the body. They lessen swelling, redness, itching, and allergic reactions. They are often used as part of the treatment for a number of different diseases, such as severe allergies or skin problems, asthma, or arthritis. Endogenous glucocorticoids and some synthetic corticoids have high affinity to the protein transcortin (also called CBG, corticosteroid-binding protein), whereas all of them bind albumin. Glucocorticoids also bind to the cytosolic glucocorticoid receptor.
has pharmacological target
activates
inhibits
type
InChIKey
InChIKey=ITRJWOMZKQRYTA-RFZYENFJSA-N
is metabolised by
Synonym
C23H30O6
2-[(1S,2R,10S,11S,14R,15S)-14-hydroxy-2,15-dimethyl-5,17-dioxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-14-yl]-2-oxoethyl acetate
xref
Wikipedia:http://en.wikipedia.org/wiki/Cortisone_acetate
PubChem Substance:46508852
RxList:http://www.rxlist.com/cgi/generic/cortisne.htm
National Drug Code Directory:0009-0015-01
ChemSpider:5543
PharmGKB:PA449130
PubChem Compound:5745
Drugs.com:http://www.drugs.com/cdi/cortisone.html
Drugs Product Database (DPD):280437
See more
See less
CASRN
50-04-4
prefixIRI
obo2:dinto_DB01380
SMILES
[H][C@@]12CC[C@](O)(C(=O)COC(C)=O)[C@@]1(C)CC(=O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C
may interact with
InChI
InChI=1S/C23H30O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-17,20,28H,4-9,11-12H2,1-3H3/t16-,17-,20+,21-,22-,23-/m0/s1
subClassOf
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display