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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
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| Id | http://purl.obolibrary.org/obo/dinto_DB01356
http://purl.obolibrary.org/obo/dinto_DB01356
|
|---|---|
| Preferred Name | lithium |
| Synonyms |
Li
lithium(1+) ion
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
lithium
|
|---|---|
| prefLabel |
lithium
|
| Definition |
Lithium was used during the 19th century to treat gout. Lithium salts such as lithium carbonate (Li2CO3), lithium citrate, and lithium orotate are mood stabilizers. They are used in the treatment of bipolar disorder, since unlike most other mood altering drugs, they counteract both mania and depression. Lithium can also be used to augment other antidepressant drugs. It is also sometimes prescribed as a preventive treatment for migraine disease and cluster headaches. The active principle in these salts is the lithium ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, in spite of its greater charge, occupying their sites in several critical neuronal enzymes and neurotransmitter receptors.
|
| DBBrand |
eskalith
lithotab
|
| ATCCode |
N05AN01
D11AX04
|
| SMILES |
[Li+]
|
| InChI |
InChI=1S/Li/q+1
|
| CASRN |
7439-93-2
|
| prefixIRI |
obo2:dinto_DB01356
|
| Synonym |
Li
lithium(1+) ion
|
| has effect |
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|
| binds | |
| InChIKey |
InChIKey=HBBGRARXTFLTSG-UHFFFAOYSA-N
|
| subClassOf | |
| may interact with |
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|
| inhibits | |
| related with | |
| type | |
| xref |
ChEBI:49713
PharmGKB:PA450243
PubChem Substance:46505392
Wikipedia:http://en.wikipedia.org/wiki/Lithium
PubChem Compound:28486
ChemSpider:26502
Drugs Product Database (DPD):236683
RxList:http://www.rxlist.com/cgi/generic/lithium.htm
Drugs.com:http://www.drugs.com/lithium.html
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|
| AHFScode |
28:28.00
92:02.00*
|
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