Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB01347
http://purl.obolibrary.org/obo/dinto_DB01347
|
|---|---|
| Preferred Name | saprisartan |
| Synonyms |
C25H22BrF3N4O4S
1-({3-bromo-2-[2-(trifluoromethane)sulfonamidophenyl]-1-benzofuran-5-yl}methyl)-4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxamide
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | saprisartan
|
|---|---|
| label | saprisartan
|
| Definition | Saprisartan is an AT1 receptor antagonist. It is based on medications of losartan s prototypical chemical structure. The mode of (functional) AT1 receptor antagonism has been characterized as insurmountable/noncompetitive for saprisartan. It is very likely that slow dissociation kinetics from the AT1 receptor underlie insurmountable antagonism.(10579749)
|
| has pharmacological target | |
| type | |
| InChIKey | InChIKey=DUEWVPTZCSAMNB-UHFFFAOYSA-N
|
| blocks | |
| Synonym | C25H22BrF3N4O4S
1-({3-bromo-2-[2-(trifluoromethane)sulfonamidophenyl]-1-benzofuran-5-yl}methyl)-4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxamide
|
| xref |
PubChem Substance:46508176
PubChem Compound:60921
PharmGKB:PA164746338
ChemSpider:54892
|
| CASRN | 146623-69-0
|
| prefixIRI | obo2:dinto_DB01347
|
| SMILES | CCC1=NC(C2CC2)=C(N1CC1=CC2=C(OC(=C2Br)C2=CC=CC=C2NS(=O)(=O)C(F)(F)F)C=C1)C(N)=O
|
| may interact with | |
| InChI | InChI=1S/C25H22BrF3N4O4S/c1-2-19-31-21(14-8-9-14)22(24(30)34)33(19)12-13-7-10-18-16(11-13)20(26)23(37-18)15-5-3-4-6-17(15)32-38(35,36)25(27,28)29/h3-7,10-11,14,32H,2,8-9,12H2,1H3,(H2,30,34)
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |