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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB01342
http://purl.obolibrary.org/obo/dinto_DB01342
|
|---|---|
| Preferred Name | forasartan |
| Synonyms |
5-[(dibutyl-1H-1,2,4-triazol-1-yl)methyl]-2-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]pyridine
C23H28N8
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | forasartan
|
|---|---|
| label | forasartan
|
| Definition | Forasartan, a specific angiotensin II antagonist, is used alone or with other antihypertensive agents to treat hypertension. Forasartan competes with angiotensin II for binding at the AT1 receptor subtype. As angiotensin II is a vasoconstrictor which also stimulates the synthesis and release of aldosterone, blockage of its effects results in a decreases in systemic vascular resistance.
|
| has pharmacological target | |
| type | |
| InChIKey | InChIKey=YONOBYIBNBCDSJ-UHFFFAOYSA-N
|
| blocks | |
| Synonym |
5-[(dibutyl-1H-1,2,4-triazol-1-yl)methyl]-2-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]pyridine
C23H28N8
|
| xref |
BindingDB:50049209
PubChem Compound:132706
ChemSpider:117146
PharmGKB:PA164776845
PubChem Substance:46505698
|
| CASRN | 145216-43-9
|
| prefixIRI | obo2:dinto_DB01342
|
| SMILES | CCCCC1=NN(CC2=CN=C(C=C2)C2=CC=CC=C2C2=NNN=N2)C(CCCC)=N1
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| may interact with | |
| InChI | InChI=1S/C23H28N8/c1-3-5-11-21-25-22(12-6-4-2)31(28-21)16-17-13-14-20(24-15-17)18-9-7-8-10-19(18)23-26-29-30-27-23/h7-10,13-15H,3-6,11-12,16H2,1-2H3,(H,26,27,29,30)
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |