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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB01320
http://purl.obolibrary.org/obo/dinto_DB01320
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|---|---|
| Preferred Name | fosphenytoin |
| Synonyms |
[(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)methoxy]phosphonic acid
C16H15N2O6P
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | fosphenytoin
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|---|---|
| label | fosphenytoin
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| DBSynonym |
fosphenytoine [inn-french]
fosphenytoin sodium
fosfenitoina [inn-spanish]
(3-phosphoryloxymethyl)phenytoin
fosphenytoinum [inn-latin]
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| ATCCode | N03AB05
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| Definition | Fosphenytoin is a water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic seizures. It works by slowing down impulses in the brain that cause seizures. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
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| has effect |
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| has pharmacological target | |
| induces | |
| inhibits | |
| type | |
| InChIKey | InChIKey=XWLUWCNOOVRFPX-UHFFFAOYSA-N
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| is metabolised by | |
| AHFScode | 28:12.12
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| Synonym |
[(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)methoxy]phosphonic acid
C16H15N2O6P
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| xref |
ChemSpider:50839
PubChem Compound:56339
Drugs Product Database (DPD):2230988
Wikipedia:http://en.wikipedia.org/wiki/Fosphenytoin
Drugs.com:http://www.drugs.com/cdi/fosphenytoin.html
PubChem Substance:46505168
RxList:http://www.rxlist.com/cgi/generic/fosphen.htm
PharmGKB:PA164746820
National Drug Code Directory:0071-4007-05
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| CASRN | 93390-81-9
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| prefixIRI | obo2:dinto_DB01320
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| related with | |
| SMILES | OP(O)(=O)OCN1C(=O)NC(C1=O)(C1=CC=CC=C1)C1=CC=CC=C1
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| may interact with |
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| InChI | InChI=1S/C16H15N2O6P/c19-14-16(12-7-3-1-4-8-12,13-9-5-2-6-10-13)17-15(20)18(14)11-24-25(21,22)23/h1-10H,11H2,(H,17,20)(H2,21,22,23)
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| DBBrand |
prodilantin
cerebyx
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| subClassOf |
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