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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
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| Preferred Name | insulin detemir | |
| Synonyms |
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| ID |
http://purl.obolibrary.org/obo/dinto_DB01307 |
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| activates | ||
| AHFScode |
68:20.08
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| ATCCode |
A10AE05
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| binds |
http://purl.obolibrary.org/obo/dinto_0217 |
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| CASRN |
169148-63-4
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| DBBrand |
levemir levemir flexpen
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| DBSynonym |
29b-[n6-(oxo-tetradecy)-l-lysine]-(1a-21a),(1b-29b)-insulin (human)
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| Definition |
Insulin detemir is a long-acting human insulin analogue used to maintain basal levels of insulin in diabetic individuals. It is produced using recombinant DNA technology in yeast cells. This insulin analogue has a 14-C fatty acid, myristic acid, bound to the lysine amino acid at position B29. The myristoyl side chain increases self-association and albumin binding. This along with slow systemic absorption from the injection site prolongs distribution of the hormone into tissues and results in a long duration of action. Novo Nordisk markets insulin detemir under the trade name Levemir.
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| has pharmacological target | ||
| induces | ||
| label |
insulin detemir
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| may interact with |
http://purl.obolibrary.org/obo/CHEBI_5000 http://purl.obolibrary.org/obo/CHEBI_4856 http://purl.obolibrary.org/obo/CHEBI_3750 http://purl.obolibrary.org/obo/CHEBI_3127 http://purl.obolibrary.org/obo/CHEBI_3441 http://purl.obolibrary.org/obo/CHEBI_2904 http://purl.obolibrary.org/obo/dinto_DB00052 |
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| modulates | ||
| prefixIRI |
obo2:dinto_DB01307
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| prefLabel |
insulin detemir
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| related with | ||
| xref |
PDRhealth:http://www.pdrhealth.com/drugs/rx/rx-mono.aspx?contentFileNam Drugs.com:http://www.drugs.com/monograph/insulin-detemir.html National Drug Code Directory:0169-3687-12 PharmGKB:PA164746470 RxList:http://www.rxlist.com/levemir-drug.htm Wikipedia:http://en.wikipedia.org/wiki/Insulin_detemir
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| subClassOf |
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