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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB01273
http://purl.obolibrary.org/obo/dinto_DB01273
|
|---|---|
| Preferred Name | varenicline |
| Synonyms |
C13H13N3
(1R,12S)-5,8,14-triazatetracyclo[10.3.1.0^{2,11}.0^{4,9}]hexadeca-2(11),3,5,7,9-pentaene
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | varenicline
|
|---|---|
| label | varenicline
|
| DBSynonym |
cp-526,555
varenicline tartrate
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| ATCCode | N07BA03
|
| Definition | Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full agonism was displayed on alpha7-receptors.
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| has effect |
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| has pharmacological target | |
| activates | |
| type | |
| InChIKey | InChIKey=JQSHBVHOMNKWFT-DTORHVGOSA-N
|
| Synonym |
C13H13N3
(1R,12S)-5,8,14-triazatetracyclo[10.3.1.0^{2,11}.0^{4,9}]hexadeca-2(11),3,5,7,9-pentaene
|
| xref |
Drugs.com:http://www.drugs.com/cdi/varenicline.html
National Drug Code Directory:0069-0471-97
PubChem Substance:46505502
Wikipedia:http://en.wikipedia.org/wiki/Varenicline
RxList:http://www.rxlist.com/cgi/generic/chantix.htm
ChemSpider:4470510
PharmGKB:PA164781343
PubChem Compound:5310966
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| CASRN | 249296-44-4
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| prefixIRI | obo2:dinto_DB01273
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| related with | |
| SMILES | [H][C@]12C[C@]([H])(CNC1)C1=CC3=NC=CN=C3C=C21
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| InChI | InChI=1S/C13H13N3/c1-2-16-13-5-11-9-3-8(6-14-7-9)10(11)4-12(13)15-1/h1-2,4-5,8-9,14H,3,6-7H2/t8-,9+
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| DBBrand |
champix
chantix
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| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |