The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_DB01251 http://purl.obolibrary.org/obo/dinto_DB01251
Preferred Name	gliquidone
Synonyms	C27H33N3O6S 3-cyclohexyl-1-({4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]benzene}sulfonyl)urea
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	gliquidone
label	gliquidone
ATCCode	A10BB08
Definition	Gliquidone is an anti-diabetic drug in the sulfonylurea class. It is used in the treatment of diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker. This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increases insulin release.
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2142 http://purl.obolibrary.org/obo/dinto_2350
inhibits	http://purl.obolibrary.org/obo/dinto_2142 http://purl.obolibrary.org/obo/dinto_2350
type	http://www.w3.org/2002/07/owl#Class
InChIKey	InChIKey=LLJFMFZYVVLQKT-UHFFFAOYSA-N
Synonym	C27H33N3O6S 3-cyclohexyl-1-({4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]benzene}sulfonyl)urea
xref	PharmGKB:PA164744895 ChemSpider:82719 PubChem Compound:91610 Wikipedia:http://en.wikipedia.org/wiki/Gliquidone PubChem Substance:46508425
CASRN	33342-05-1
prefixIRI	obo2:dinto_DB01251
SMILES	COC1=CC2=C(C=C1)C(C)(C)C(=O)N(CCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1)C2=O
InChI	InChI=1S/C27H33N3O6S/c1-27(2)23-14-11-20(36-3)17-22(23)24(31)30(25(27)32)16-15-18-9-12-21(13-10-18)37(34,35)29-26(33)28-19-7-5-4-6-8-19/h9-14,17,19H,4-8,15-16H2,1-3H3,(H2,28,29,33)
DBBrand	glurenorm
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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