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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB01225
http://purl.obolibrary.org/obo/dinto_DB01225
|
|---|---|
| Preferred Name | enoxaparin |
| Synonyms |
C26H42N2O37S5
3-[(5-{[6-carboxy-4,5-dihydroxy-3-(sulfooxy)oxan-2-yl]oxy}-6-(hydroxymethyl)-3-(sulfoamino)-4-(sulfooxy)oxan-2-yl)oxy]-6-({5-acetamido-4,6-dihydroxy-2-[(sulfooxy)methyl]oxan-3-yl}oxy)-4-hydroxy-5-(sulfooxy)oxane-2-carboxylic acid
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | enoxaparin
|
|---|---|
| label | enoxaparin
|
| DBSynonym |
lmwh
low molecular weight heparin
|
| ATCCode |
B01AB01
B01AB05
|
| Definition | Enoxaparin is a low molecular weight heparin. Enoxaparin is used to prevent and treat deep vein thrombosis or pulmonary embolism, and is given as a subcutaneous injection. Enoxaparin binds to and accelerates the activity of antithrombin III. By activating antithrombin III, enoxaparin preferentially potentiates the inhibition of coagulation factors Xa and IIa. Factor Xa catalyzes the conversion of prothrombin to thrombin, so enoxaparin s inhibition of this process results in decreased thrombin and ultimately the prevention of fibrin clot formation. Low molecular weight heparins are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin.
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| has effect |
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| has pharmacological target | |
| inhibits | |
| type | |
| InChIKey | InChIKey=HTTJABKRGRZYRN-UHFFFAOYSA-N
|
| AHFScode |
92:00.00
20:12.04.16
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| Synonym | C26H42N2O37S5
3-[(5-{[6-carboxy-4,5-dihydroxy-3-(sulfooxy)oxan-2-yl]oxy}-6-(hydroxymethyl)-3-(sulfoamino)-4-(sulfooxy)oxan-2-yl)oxy]-6-({5-acetamido-4,6-dihydroxy-2-[(sulfooxy)methyl]oxan-3-yl}oxy)-4-hydroxy-5-(sulfooxy)oxane-2-carboxylic acid
|
| xref |
Drugs.com:http://www.drugs.com/cdi/enoxaparin.html
ChemSpider:751
PharmGKB:PA449463
PubChem Substance:46507450
National Drug Code Directory:0075-2915-01
Drugs Product Database (DPD):2242692
PubChem Compound:772
Wikipedia:http://en.wikipedia.org/wiki/Enoxaparin
RxList:http://www.rxlist.com/cgi/generic3/lovenox.htm
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| CASRN | 9005-49-6
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| prefixIRI | obo2:dinto_DB01225
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| related with | |
| SMILES | CC(=O)NC1C(O)OC(COS(O)(=O)=O)C(OC2OC(C(OC3OC(CO)C(OC4OC(C(O)C(O)C4OS(O)(=O)=O)C(O)=O)C(OS(O)(=O)=O)C3NS(O)(=O)=O)C(O)C2OS(O)(=O)=O)C(O)=O)C1O
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| may interact with | |
| InChI | InChI=1S/C26H42N2O37S5/c1-4(30)27-7-9(31)13(6(56-23(7)39)3-55-67(43,44)45)58-26-19(65-70(52,53)54)12(34)16(20(62-26)22(37)38)60-24-8(28-66(40,41)42)15(63-68(46,47)48)14(5(2-29)57-24)59-25-18(64-69(49,50)51)11(33)10(32)17(61-25)21(35)36/h5-20,23-26,28-29,31-34,39H,2-3H2,1H3,(H,27,30)(H,35,36)(H,37,38)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)
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| DBBrand |
lovenox hp
lovenox
clexane
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |