The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_DB01190 http://purl.obolibrary.org/obo/dinto_DB01190
Preferred Name	clindamycin
Synonyms	(2S,4R)-N-{2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl}-1-methyl-4-propylpyrrolidine-2-carboxamide C18H33ClN2O5S
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	clindamycin
label	clindamycin
DBSynonym	clindamycine [inn-french] clindamycine [french] clindamycin phosphate clindamycinum [inn-latin] clindamycin hydrochloride clindamicina [inn-spanish] See more See less
ATCCode	D10AF01 G01AA10 J01FF01
Definition	Clindamycin is a semisynthetic lincosamide antibiotic that has largely replaced lincomycin due to an improved side effect profile. Clindamycin inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits. It may be bacteriostatic or bactericidal depending on the organism and drug concentration.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0001186 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0001449 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000103 http://purl.obolibrary.org/obo/OAE_0000454 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000386 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0001234 http://purl.obolibrary.org/obo/OAE_0000498 http://purl.obolibrary.org/obo/OAE_0001295 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000894 http://purl.obolibrary.org/obo/OAE_0000243 http://purl.obolibrary.org/obo/OAE_0001004 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0001499 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0001434 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0001356 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0000358 http://purl.obolibrary.org/obo/OAE_0000488 http://purl.obolibrary.org/obo/OAE_0001497 http://purl.obolibrary.org/obo/OAE_0000402 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2857 http://purl.obolibrary.org/obo/dinto_2752
inhibits	http://purl.obolibrary.org/obo/dinto_2857 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_2752
type	http://www.w3.org/2002/07/owl#Class
InChIKey	InChIKey=KDLRVYVGXIQJDK-NOWPCOIGSA-N
is metabolised by	http://purl.obolibrary.org/obo/dinto_0901
AHFScode	08:12.28.20 84:04.04
Synonym	(2S,4R)-N-{2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl}-1-methyl-4-propylpyrrolidine-2-carboxamide C18H33ClN2O5S
xref	Drugs.com:http://www.drugs.com/clindamycin.html RxList:http://www.rxlist.com/cgi/generic2/clindam.htm Drugs Product Database (DPD):2258331 ChEBI:3745 PubChem Compound:29029 PharmGKB:PA449035 ChemSpider:27005 Wikipedia:http://en.wikipedia.org/wiki/Clindamycin PubChem Substance:46506073 PDB:CLY National Drug Code Directory:0009-0331-02 See more See less
CASRN	18323-44-9
prefixIRI	obo2:dinto_DB01190
SMILES	CCC[C@@H]1C[C@H](N(C)C1)C(=O)NC(C(C)Cl)[C@H]1O[C@H](SC)[C@H](O)[C@@H](O)[C@H]1O
may interact with	http://purl.obolibrary.org/obo/CHEBI_9939 http://purl.obolibrary.org/obo/dinto_DB01338 http://purl.obolibrary.org/obo/CHEBI_4031 http://purl.obolibrary.org/obo/dinto_DB01336 http://purl.obolibrary.org/obo/dinto_DB01226 http://purl.obolibrary.org/obo/CHEBI_45652 http://purl.obolibrary.org/obo/dinto_DB01370 http://purl.obolibrary.org/obo/dinto_DB01574 http://purl.obolibrary.org/obo/dinto_DB01575 http://purl.obolibrary.org/obo/dinto_DB01375 http://purl.obolibrary.org/obo/CHEBI_8884 http://purl.obolibrary.org/obo/CHEBI_7907 http://purl.obolibrary.org/obo/CHEBI_9774 http://purl.obolibrary.org/obo/CHEBI_2914 http://purl.obolibrary.org/obo/CHEBI_4707 See more See less
InChI	InChI=1S/C18H33ClN2O5S/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25)/t9?,10-,11+,12?,13+,14-,15-,16-,18-/m1/s1
DBBrand	chlolincocin residerm a zindaclin dalacin c cleocin pediatric clindets sobelin cleocin t cleocin phosphate evoclin dalacin c phosphate cleocin hcl cleocin t topical solution cleocin t gel cleocin cleocin t lotion clinda-derm clinimycin dalacin t topical solution dalacin c flavored granules See more See less
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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