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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB01083
http://purl.obolibrary.org/obo/dinto_DB01083
|
|---|---|
| Preferred Name | orlistat |
| Synonyms |
(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl (2S)-2-formamido-4-methylpentanoate
C29H53NO5
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | orlistat
|
|---|---|
| label | orlistat
|
| DBSynonym |
orlipastatum [inn-latin]
tetrahydrolipstatin
orlipastat
(-)-tetrahydrolipstatin
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| ATCCode | A08AB01
|
| Definition | Orlistat is a drug designed to treat obesity. Its primary function is preventing the absorption of fats from the human diet, thereby reducing caloric intake. Orlistat works by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine. Without this enzyme, triglycerides from the diet are prevented from being hydrolyzed into absorbable free fatty acids and are excreted undigested.
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| has effect |
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| has pharmacological target | |
| induces | |
| inhibits | |
| type | |
| InChIKey | InChIKey=AHLBNYSZXLDEJQ-FWEHEUNISA-N
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| AHFScode | 56:92.00
|
| Synonym |
(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl (2S)-2-formamido-4-methylpentanoate
C29H53NO5
|
| xref |
BindingDB:24567
PharmGKB:PA164776864
Wikipedia:http://en.wikipedia.org/wiki/Orlistat
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/xen1529.shtml
National Drug Code Directory:0004-0256-52
Drugs Product Database (DPD):2240325
PubChem Substance:46508309
RxList:http://www.rxlist.com/cgi/generic/orlistat.htm
ChemSpider:2298564
Drugs.com:http://www.drugs.com/orlistat.html
PubChem Compound:3034010
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| CASRN | 96829-58-2
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| prefixIRI | obo2:dinto_DB01083
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| SMILES | CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O
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| may interact with |
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| InChI | InChI=1S/C29H53NO5/c1-5-7-9-11-12-13-14-15-16-18-24(34-29(33)26(30-22-31)20-23(3)4)21-27-25(28(32)35-27)19-17-10-8-6-2/h22-27H,5-21H2,1-4H3,(H,30,31)/t24-,25-,26-,27-/m0/s1
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| DBBrand |
xenical
alli
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| subClassOf |
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