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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB01018
http://purl.obolibrary.org/obo/dinto_DB01018
|
|---|---|
| Preferred Name | guanfacine |
| Synonyms |
N-carbamimidoyl-2-(2,6-dichlorophenyl)acetamide
C9H9Cl2N3O
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | guanfacine
|
|---|---|
| label | guanfacine
|
| DBSynonym |
guanfacine hcl
spd 503
guanfacina [inn-spanish]
guanfacinum [inn-latin]
guanfacine hydrochloride
|
| ATCCode | C02AC02
|
| Definition | A centrally acting antihypertensive agent. The drug lowers both systolic and diastolic blood pressure by activating the central nervous system alpha-2 adrenoreceptors, which results in reduced sympathetic outflow leading to reduced vascular tone. Its adverse reactions include dry mouth, sedation, and constipation. [PubChem]
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| has effect |
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| has pharmacological target | |
| activates | |
| type | |
| InChIKey | InChIKey=INJOMKTZOLKMBF-UHFFFAOYSA-N
|
| is metabolised by | |
| Synonym |
N-carbamimidoyl-2-(2,6-dichlorophenyl)acetamide
C9H9Cl2N3O
|
| xref |
RxList:http://www.rxlist.com/cgi/generic3/guanfacine.htm
IUPHAR:522
PubChem Compound:3519
Drugs.com:http://www.drugs.com/cdi/guanfacine.html
Wikipedia:http://en.wikipedia.org/wiki/Guanfacine
ChemSpider:3399
National Drug Code Directory:55567-051-18
PubChem Substance:46506169
PharmGKB:PA449825
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/gua1657.shtml
Guide To Pharmacology:522
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| CASRN | 29110-47-2
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| prefixIRI | obo2:dinto_DB01018
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| SMILES | NC(=N)NC(=O)CC1=C(Cl)C=CC=C1Cl
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| may interact with | |
| InChI | InChI=1S/C9H9Cl2N3O/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13/h1-3H,4H2,(H4,12,13,14,15)
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| DBBrand |
tenex
intuniv
estulic
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| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |