The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Id http://purl.obolibrary.org/obo/dinto_DB00944
http://purl.obolibrary.org/obo/dinto_DB00944
Preferred Name

demecarium
Synonyms
C32H52N4O4
N,N,N-trimethyl-3-{[methyl(10-{methyl[3-(trimethylazaniumyl)phenoxycarbonyl]amino}decyl)carbamoyl]oxy}anilinium
Type http://www.w3.org/2002/07/owl#Class

All Properties

prefLabel
demecarium
label
demecarium
DBSynonym
demecarium bromide
ATCCode
S01EB04
Definition
Demecarium bromid is an indirect-acting parasympathomimetic agent that is used to treat glaucoma. It is a cholinesterase inhibitor or an anticholinesterase. Cholinesterase inhibitors prolong the effect of acetylcholine, which is released at the neuroeffector junction of parasympathetic postganglion nerves, by inactivating the cholinesterases that break it down. Demecarium inactivates both pseudocholinesterase and acetylcholinesterase. In the eye, this causes constriction of the iris sphincter muscle (causing miosis) and the ciliary muscle. The outflow of the aqueous humor is facilitated, which leads to a reduction in intraocular pressure.
has pharmacological target
inhibits
type
InChIKey
InChIKey=RWZVPVOZTJJMNU-UHFFFAOYSA-N
Synonym
C32H52N4O4
N,N,N-trimethyl-3-{[methyl(10-{methyl[3-(trimethylazaniumyl)phenoxycarbonyl]amino}decyl)carbamoyl]oxy}anilinium
xref
RxList:http://www.rxlist.com/cgi/generic2/demecarium.htm
PubChem Substance:46507824
Wikipedia:http://en.wikipedia.org/wiki/Demecarium_bromide
Drugs.com:http://www.drugs.com/mtm/demecarium-bromide-ophthalmic.html
PubChem Compound:5965
PharmGKB:PA164745610
See more
See less
CASRN
56-94-0
prefixIRI
obo2:dinto_DB00944
SMILES
CN(CCCCCCCCCCN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C
may interact with
InChI
InChI=1S/C32H52N4O4/c1-33(31(37)39-29-21-17-19-27(25-29)35(3,4)5)23-15-13-11-9-10-12-14-16-24-34(2)32(38)40-30-22-18-20-28(26-30)36(6,7)8/h17-22,25-26H,9-16,23-24H2,1-8H3/q+2
subClassOf
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display