loading...| Preferred Name | azacitidine | |
| Synonyms |
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one C8H12N4O5 |
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| ID |
http://purl.obolibrary.org/obo/dinto_DB00928 |
|
| binds |
http://purl.obolibrary.org/obo/dinto_4090 http://purl.obolibrary.org/obo/dinto_2873 |
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| CASRN |
320-67-2 |
|
| DBBrand |
mylosar vidaza ladakamycin |
|
| DBSynonym |
azacitidina [inn-spanish] azacitidinum [inn-latin] 5 azc azacytidine |
|
| Definition |
A pyrimidine nucleoside analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primarily into RNA. Azacytidine has been used as an antineoplastic agent. [PubChem] |
|
| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_4090 |
|
| InChI |
InChI=1S/C8H12N4O5/c9-7-10-2-12(8(16)11-7)6-5(15)4(14)3(1-13)17-6/h2-6,13-15H,1H2,(H2,9,11,16)/t3-,4-,5-,6-/m1/s1 |
|
| InChIKey |
InChIKey=NMUSYJAQQFHJEW-KVTDHHQDSA-N |
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| inhibits | ||
| is metabolised by | ||
| is substrate of | ||
| label |
azacitidine |
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| may interact with | ||
| prefixIRI |
obo2:dinto_DB00928 |
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| prefLabel |
azacitidine |
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| related with | ||
| SMILES |
NC1=NC(=O)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |
|
| Synonym |
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one C8H12N4O5 |
|
| xref |
RxList:http://www.rxlist.com/cgi/generic3/vidaza.htm ChEBI:2038 National Drug Code Directory:67211-102-01 PubChem Substance:46509032 ChemSpider:9072 PharmGKB:PA451996 Wikipedia:http://en.wikipedia.org/wiki/Azacitidine PubChem Compound:9444 |
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| subClassOf |