The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_DB00920 http://purl.obolibrary.org/obo/dinto_DB00920
Preferred Name	ketotifen
Synonyms	2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0^{3,7}]tetradeca-1(10),3(7),4,11,13-pentaen-8-one C19H19NOS
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	ketotifen
label	ketotifen
DBSynonym	ketotifene [inn-french] ketotifen fumarate ketotifenum [inn-latin] ketotifeno [inn-spanish] ketotifene fumarate
ATCCode	R06AX17 S01GX08
Definition	A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis. [PubChem]
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0001025 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001105 http://purl.obolibrary.org/obo/OAE_0001515 http://purl.obolibrary.org/obo/OAE_0001425 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000402 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_3498 http://purl.obolibrary.org/obo/dinto_4063 http://purl.obolibrary.org/obo/dinto_1436 http://purl.obolibrary.org/obo/dinto_1439 http://purl.obolibrary.org/obo/dinto_3125 http://purl.obolibrary.org/obo/dinto_1071 http://purl.obolibrary.org/obo/dinto_0074 http://purl.obolibrary.org/obo/dinto_3980 http://purl.obolibrary.org/obo/dinto_2945 See more See less
inhibits	http://purl.obolibrary.org/obo/dinto_3498 http://purl.obolibrary.org/obo/dinto_4063 http://purl.obolibrary.org/obo/dinto_1436 http://purl.obolibrary.org/obo/dinto_1439 http://purl.obolibrary.org/obo/dinto_0433 http://purl.obolibrary.org/obo/dinto_3125 http://purl.obolibrary.org/obo/dinto_0074 http://purl.obolibrary.org/obo/dinto_3980 http://purl.obolibrary.org/obo/dinto_2945 See more See less
type	http://www.w3.org/2002/07/owl#Class
InChIKey	InChIKey=ZCVMWBYGMWKGHF-UHFFFAOYSA-N
blocks	http://purl.obolibrary.org/obo/dinto_1071
AHFScode	04:00.00 52:02.00 04:92.00
Synonym	2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0^{3,7}]tetradeca-1(10),3(7),4,11,13-pentaen-8-one C19H19NOS
xref	Wikipedia:http://en.wikipedia.org/wiki/Ketotifen National Drug Code Directory:50580-732-05 RxList:http://www.rxlist.com/cgi/generic/ketotifen.htm ChemSpider:3695 PharmGKB:PA450152 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/zad1598.shtml Drugs.com:http://www.drugs.com/cdi/ketotifen-drops.html BindingDB:50002087 PubChem Substance:46508921 Drugs Product Database (DPD):2242324 PubChem Compound:3827 See more See less
CASRN	34580-14-8
prefixIRI	obo2:dinto_DB00920
SMILES	CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
may interact with	http://purl.obolibrary.org/obo/dinto_DB00209 http://purl.obolibrary.org/obo/dinto_DB00427 http://purl.obolibrary.org/obo/CHEBI_27796 http://purl.obolibrary.org/obo/dinto_DB00382
InChI	InChI=1S/C19H19NOS/c1-20-9-6-13(7-10-20)18-15-5-3-2-4-14(15)12-17(21)19-16(18)8-11-22-19/h2-5,8,11H,6-7,9-10,12H2,1H3
DBBrand	zaditor ketotifen
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

Add comment

Add proposal

Subscribe to notes emails

Delete	Subject	Author	Type	Created
No notes to display