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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB00822
http://purl.obolibrary.org/obo/dinto_DB00822
|
|---|---|
| Preferred Name | disulfiram |
| Synonyms |
N,N-diethyl[(diethylcarbamothioyl)disulfanyl]carbothioamide
C10H20N2S4
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | disulfiram
|
|---|---|
| label | disulfiram
|
| DBSynonym |
ttd
tatd
tetraethylthiram disulphide
tetraethylthiuram disulphide
disulphuram
tetraethylthiuram sulfide
tetd
dupon 4472
tetraethylthiuran disulfide
tetraethylthiuram disulfide
usaf b-33
tetraethylthiram disulfide
disulfuram
dupont fungicide 4472
tetraethylthiuram
tetraethylthioperoxydicarbonic diamide
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|
| ATCCode |
N07BB01
P03AA04
|
| Definition | A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase. [PubChem]
|
| has effect |
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| has pharmacological target | |
| inhibits | |
| type | |
| InChIKey | InChIKey=AUZONCFQVSMFAP-UHFFFAOYSA-N
|
| is metabolised by | |
| Synonym |
N,N-diethyl[(diethylcarbamothioyl)disulfanyl]carbothioamide
C10H20N2S4
|
| xref |
ChemSpider:3005
National Drug Code Directory:49884-153-01
ChEBI:4659
Wikipedia:http://en.wikipedia.org/wiki/Disulfiram
RxList:http://www.rxlist.com/cgi/generic/disulfiram.htm
PubChem Substance:46506008
Drugs.com:http://www.drugs.com/cdi/disulfiram.html
PharmGKB:PA449376
Drugs Product Database (DPD):2534
PubChem Compound:3117
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|
| CASRN | 97-77-8
|
| prefixIRI | obo2:dinto_DB00822
|
| SMILES | CCN(CC)C(=S)SSC(=S)N(CC)CC
|
| may interact with |
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| InChI | InChI=1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3
|
| DBBrand |
ekagom tetds
refusal
cronetal
ethyl thiram
ro-sulfiram
tts x
anti-ethyl
ekagom dtet
super rodiatox
ethyl thiurad
thireranide
antikol
stopethyl
antetil
abstinil
anticol
soxinol tet
accel tet-r
etabus
antaetil
perkait tetd
tetraetil
abstensil
ethyl tuex
ancazide et
antetan
alk-aubs
tetidis
alcophobin
nocceler tet
antivitium
teturam
abstinyl
tts
accel tet
antadix
perkacit tetd
bonibal
nocceler tet-g
antaethan
thiocid
akrochem tetd
disulfram
ethyldithiourame
anthethyl
tetradin
stopetyl
thiophos
antietil
antaenyl
ethyl tuads rodform
sanceler tet
tetradine
antietanol
ethyldithiurame
contralin
esperal
dicupral
antabus
aversan
espenal
nocbin
averzan
sanceler tet-g
ekagom teds
ethyl tuads
tenutex
teturamin
stopaethyl
anteyl
antaethyl
noxal
antalcol
exhoran
tenurid
krotenal
hoca
antiaethan
contrapot
disetil
tillram
ekaland tetd
antabuse
exhorran
ephorran
stopety
tiuram
disulfan
ethyl thiudad
gababentin
etyl tuex
antethyl
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| subClassOf |
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