The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_DB00806 http://purl.obolibrary.org/obo/dinto_DB00806
Preferred Name	pentoxifylline
Synonyms	C13H18N4O3 3,7-dimethyl-1-(5-oxohexyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	pentoxifylline
label	pentoxifylline
DBSynonym	eht0201
ATCCode	C04AD03
Definition	A methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production. [PubChem]
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000335 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0001025 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000476 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0001168 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000454 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0000517 http://purl.obolibrary.org/obo/OAE_0000502 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000473 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000438 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0002122 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000487 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000242 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000811 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_3607 http://purl.obolibrary.org/obo/dinto_1637 http://purl.obolibrary.org/obo/dinto_4063 http://purl.obolibrary.org/obo/dinto_0074 http://purl.obolibrary.org/obo/dinto_0932
inhibits	http://purl.obolibrary.org/obo/dinto_1637 http://purl.obolibrary.org/obo/dinto_4063 http://purl.obolibrary.org/obo/dinto_0074 http://purl.obolibrary.org/obo/dinto_0152
type	http://www.w3.org/2002/07/owl#Class
InChIKey	InChIKey=BYPFEZZEUUWMEJ-UHFFFAOYSA-N
is metabolised by	http://purl.obolibrary.org/obo/dinto_2651
blocks	http://purl.obolibrary.org/obo/dinto_3607 http://purl.obolibrary.org/obo/dinto_0932
AHFScode	20:24.00
Synonym	C13H18N4O3 3,7-dimethyl-1-(5-oxohexyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione
xref	National Drug Code Directory:0378-0357-01 RxList:http://www.rxlist.com/cgi/generic/pentox.htm BindingDB:10850 ChemSpider:4578 Drugs.com:http://www.drugs.com/cdi/pentoxifylline.html PubChem Substance:46505940 Drugs Product Database (DPD):1968432 Wikipedia:http://en.wikipedia.org/wiki/Pentoxifylline PharmGKB:PA450864 PubChem Compound:4740 See more See less
CASRN	6493-05-6
prefixIRI	obo2:dinto_DB00806
SMILES	CN1C=NC2=C1C(=O)N(CCCCC(C)=O)C(=O)N2C
may interact with	http://purl.obolibrary.org/obo/dinto_DB01303 http://purl.obolibrary.org/obo/dinto_DB01223 http://purl.obolibrary.org/obo/CHEBI_53766 http://purl.obolibrary.org/obo/CHEBI_133809 http://purl.obolibrary.org/obo/CHEBI_4728 http://purl.obolibrary.org/obo/CHEBI_10033 http://purl.obolibrary.org/obo/CHEBI_4513 http://purl.obolibrary.org/obo/dinto_DB00046 http://purl.obolibrary.org/obo/CHEBI_28177 See more See less
InChI	InChI=1S/C13H18N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8H,4-7H2,1-3H3
DBBrand	pentoxil pentoxiphyllium trental durapental vazofirin dimethyloxohexylxanthine pentoxyphylline torental pentoxyphyline pentoxyfylline rentylin oxpentifylline pentoxifyllin azupentat See more See less
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

Add comment

Add proposal

Subscribe to notes emails

Delete	Subject	Author	Type	Created
No notes to display