The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

gentamicin
Synonyms

C21H43N5O7

2-{[4,6-diamino-3-({3-amino-6-[1-(methylamino)ethyl]oxan-2-yl}oxy)-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol
ID

http://purl.obolibrary.org/obo/dinto_DB00798
AHFScode

84:04.04

52:04.04

08:12.02
ATCCode

D06AX07

S03AA06

S02AA14

J01GB03

S01AA11
binds

http://purl.obolibrary.org/obo/dinto_0520

http://purl.obolibrary.org/obo/dinto_1191

http://purl.obolibrary.org/obo/dinto_2863

http://purl.obolibrary.org/obo/dinto_3225
CASRN

1403-66-3
DBBrand

g-mycin

genoptic liquifilm

garamycin otic solution

g-myticin

jenamicin

gentamcin sulfate

gentak

spectro-genta

apogen

gentamar

genoptic s.o.p.

ocu-mycin

alcomicin

bristagen

gentacidin

garamycin

gentafair

u-gencin
Definition

A complex of three different closely related aminoglycoside sulfates, Gentamicins C1, C2, and C1(subA), obtained from Micromonospora purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit protein synthesis (genetic translation). [PubChem]
has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0001059

http://purl.obolibrary.org/obo/OAE_0001505

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000512

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000545

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000418

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000333

http://purl.obolibrary.org/obo/OAE_0000197

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000920

http://purl.obolibrary.org/obo/OAE_0000608

http://purl.obolibrary.org/obo/OAE_0000403

http://purl.obolibrary.org/obo/OAE_0001055

http://purl.obolibrary.org/obo/OAE_0000454

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000551

http://purl.obolibrary.org/obo/OAE_0000268

http://purl.obolibrary.org/obo/OAE_0001341

http://purl.obolibrary.org/obo/OAE_0000494

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000607

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000405

http://purl.obolibrary.org/obo/OAE_0000306

http://purl.obolibrary.org/obo/OAE_0000194

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000185

http://purl.obolibrary.org/obo/OAE_0000487

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0001035

http://purl.obolibrary.org/obo/OAE_0001418

http://purl.obolibrary.org/obo/OAE_0001366

http://purl.obolibrary.org/obo/OAE_0000480
has pharmacological target

http://purl.obolibrary.org/obo/dinto_1191

http://purl.obolibrary.org/obo/dinto_2863
InChI

InChI=1S/C21H43N5O7/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20/h9-20,25-29H,5-8,22-24H2,1-4H3
InChIKey

InChIKey=CEAZRRDELHUEMR-UHFFFAOYSA-N
inhibits

http://purl.obolibrary.org/obo/dinto_0520
label

gentamicin
may interact with

http://purl.obolibrary.org/obo/CHEBI_553473

http://purl.obolibrary.org/obo/CHEBI_3213

http://purl.obolibrary.org/obo/CHEBI_9939

http://purl.obolibrary.org/obo/CHEBI_3499

http://purl.obolibrary.org/obo/CHEBI_3491

http://purl.obolibrary.org/obo/CHEBI_3493

http://purl.obolibrary.org/obo/CHEBI_3495

http://purl.obolibrary.org/obo/dinto_DB01338

http://purl.obolibrary.org/obo/CHEBI_3480

http://purl.obolibrary.org/obo/CHEBI_474053

http://purl.obolibrary.org/obo/dinto_DB03450

http://purl.obolibrary.org/obo/CHEBI_61049

http://purl.obolibrary.org/obo/CHEBI_9513

http://purl.obolibrary.org/obo/dinto_DB01336

http://purl.obolibrary.org/obo/dinto_DB01226

http://purl.obolibrary.org/obo/dinto_DB00214

http://purl.obolibrary.org/obo/CHEBI_45652

http://purl.obolibrary.org/obo/CHEBI_204928

http://purl.obolibrary.org/obo/CHEBI_3508

http://purl.obolibrary.org/obo/CHEBI_29007

http://purl.obolibrary.org/obo/dinto_DB01112

http://purl.obolibrary.org/obo/CHEBI_554446

http://purl.obolibrary.org/obo/CHEBI_8884

http://purl.obolibrary.org/obo/CHEBI_7907

http://purl.obolibrary.org/obo/CHEBI_9774

http://purl.obolibrary.org/obo/CHEBI_209807

http://purl.obolibrary.org/obo/CHEBI_2914

http://purl.obolibrary.org/obo/CHEBI_9587

http://purl.obolibrary.org/obo/CHEBI_4876

http://purl.obolibrary.org/obo/CHEBI_59662

http://purl.obolibrary.org/obo/CHEBI_47426

http://purl.obolibrary.org/obo/CHEBI_27899

http://purl.obolibrary.org/obo/CHEBI_3547

http://purl.obolibrary.org/obo/CHEBI_4707
prefixIRI

obo2:dinto_DB00798
prefLabel

gentamicin
related with

http://purl.obolibrary.org/obo/dinto_1191

http://purl.obolibrary.org/obo/dinto_2863

http://purl.obolibrary.org/obo/dinto_3225
SMILES

CNC(C)C1CCC(N)C(OC2C(N)CC(N)C(OC3OCC(C)(O)C(NC)C3O)C2O)O1
Synonym

C21H43N5O7

2-{[4,6-diamino-3-({3-amino-6-[1-(methylamino)ethyl]oxan-2-yl}oxy)-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol
xref

IUPHAR:2427

Drugs Product Database (DPD):776521

ChemSpider:3348

PharmGKB:PA449753

PubChem Compound:3467

PubChem Substance:46506523

Drugs.com:http://www.drugs.com/cdi/gentamicin-drops.html

Wikipedia:http://en.wikipedia.org/wiki/Gentamicin

Guide To Pharmacology:2427

PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/gar1187.shtml

RxList:http://www.rxlist.com/cgi/generic2/pedgenta.htm

National Drug Code Directory:17478-283-10

ChEBI:17833
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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Mapping To Ontology Source
http://purl.bioontology.org/ontology/CSP/0191-7691 CRISP LOOM
http://purl.obolibrary.org/obo/DRON_01002946 DRON LOOM
http://purl.obolibrary.org/obo/DRON_01002946 DDSS LOOM
http://purl.bioontology.org/ontology/ATC/S03AA06 ATC LOOM
http://purl.bioontology.org/ontology/ATC/J01GB03 ATC LOOM
http://purl.obolibrary.org/obo/DRON_00730841 PDRO LOOM
http://purl.bioontology.org/ontology/VANDF/4019765 VANDF LOOM
http://www.phoc.org.cn/pmo/class/PMO_00025743 PMAPP-PMO LOOM
http://www.co-ode.org/ontologies/galen#Gentamicin GALEN LOOM
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Gentamicin SEPON LOOM
http://purl.bioontology.org/ontology/RXNORM/1596450 RXNORM LOOM
http://purl.bioontology.org/ontology/ATC/S02AA14 ATC LOOM
http://purl.bioontology.org/ontology/CPT/80170 CPT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0017436 OCHV LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C519 NCIT LOOM
http://purl.obolibrary.org/obo/NCIT_C519 BERO LOOM
http://purl.obolibrary.org/obo/NCIT_C519 SCDO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039250 PDQ LOOM
http://purl.obolibrary.org/obo/CHEBI_17833 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_17833 TXPO LOOM
http://purl.jp/bio/4/id/200906052661342087 IOBC LOOM
http://purl.bioontology.org/ontology/SNMI/C-52530 SNMI LOOM
https://go.drugbank.com/drugs/DB00798 MDM LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004260 LOINC LOOM
http://purl.bioontology.org/ontology/ATC/D06AX07 ATC LOOM
http://purl.jp/bio/10/gmo/GMO_001989 GMO LOOM
http://purl.bioontology.org/ontology/NDDF/004898 NDDF LOOM
http://id.nlm.nih.gov/mesh/D005839 MDM LOOM
http://purl.bioontology.org/ontology/LNC/LP15747-6 LOINC LOOM
http://www.drugbank.ca/drugs/DB00798 FTC LOOM
http://purl.obolibrary.org/obo/ARO_3007382 ARO LOOM
http://purl.obolibrary.org/obo/HIO_0000278 HIO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147856 NDFRT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387321007 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/ATC/S01AA11 ATC LOOM