The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_DB00691 http://purl.obolibrary.org/obo/dinto_DB00691
Preferred Name	moexipril
Synonyms	C27H34N2O7 (3S)-2-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	moexipril
label	moexipril
DBSynonym	moexipril hydrochloride moexiprilum [inn-latin] moexipril hcl
ATCCode	C09AA13
Definition	Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0001046 http://purl.obolibrary.org/obo/OAE_0000567 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000038 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0002122 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000647 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0001309 http://purl.obolibrary.org/obo/OAE_0000534 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000350 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2574 http://purl.obolibrary.org/obo/dinto_2130
inhibits	http://purl.obolibrary.org/obo/dinto_2574 http://purl.obolibrary.org/obo/dinto_2130
type	http://www.w3.org/2002/07/owl#Class
InChIKey	InChIKey=UWWDHYUMIORJTA-HSQYWUDLSA-N
AHFScode	24:32.04
Synonym	C27H34N2O7 (3S)-2-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
xref	PharmGKB:PA164769059 Drugs.com:http://www.drugs.com/cdi/moexipril.html BindingDB:50084673 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/uni1468.shtml PubChem Compound:91270 Wikipedia:http://en.wikipedia.org/wiki/Moexipril PubChem Substance:46508441 National Drug Code Directory:0574-0110-01 ChemSpider:82418 RxList:http://www.rxlist.com/cgi/generic2/moexip.htm See more See less
CASRN	103775-10-6
prefixIRI	obo2:dinto_DB00691
is transported by	http://purl.obolibrary.org/obo/dinto_4065 http://purl.obolibrary.org/obo/dinto_2004
SMILES	CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N1CC2=CC(OC)=C(OC)C=C2C[C@H]1C(O)=O
may interact with	http://purl.obolibrary.org/obo/dinto_DB00384 http://purl.obolibrary.org/obo/dinto_DB01356 http://purl.obolibrary.org/obo/CHEBI_50861 http://purl.obolibrary.org/obo/CHEBI_63629 http://purl.obolibrary.org/obo/dinto_DB01369 http://purl.obolibrary.org/obo/CHEBI_2639 http://purl.obolibrary.org/obo/CHEBI_68564 http://purl.obolibrary.org/obo/CHEBI_68845 http://purl.obolibrary.org/obo/dinto_DB01345 See more See less
InChI	InChI=1S/C27H34N2O7/c1-5-36-27(33)21(12-11-18-9-7-6-8-10-18)28-17(2)25(30)29-16-20-15-24(35-4)23(34-3)14-19(20)13-22(29)26(31)32/h6-10,14-15,17,21-22,28H,5,11-13,16H2,1-4H3,(H,31,32)/t17-,21-,22-/m0/s1
DBBrand	univasc
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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