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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB00684
http://purl.obolibrary.org/obo/dinto_DB00684
|
|---|---|
| Preferred Name | tobramycin |
| Synonyms |
(2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)oxane-3,5-diol
C18H37N5O9
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | tobramycin
|
|---|---|
| label | tobramycin
|
| DBSynonym |
tobramycin sulfate
3'-deoxykanamycin b
tobramycin solution for inhalation
sprc-ab01
|
| ATCCode |
S01AA12
J01GB01
|
| Definition | An aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius. It is effective against gram-negative bacteria, especially the pseudomonas species. It is a 10% component of the antibiotic complex, nebramycin, produced by the same species. [PubChem]
|
| has effect |
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| has pharmacological target | |
| inhibits | |
| type | |
| InChIKey | InChIKey=NLVFBUXFDBBNBW-PBSUHMDJSA-N
|
| is metabolised by | |
| AHFScode |
52:04.04
08:12.02
|
| Synonym | (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)oxane-3,5-diol
C18H37N5O9
|
| xref |
RxList:http://www.rxlist.com/cgi/generic/tobi.htm
ChemSpider:33377
ChEBI:28864
Wikipedia:http://en.wikipedia.org/wiki/Tobramycin
PharmGKB:PA451704
PDB:TOY
BindingDB:50090265
Drugs.com:http://www.drugs.com/cdi/tobramycin-drops.html
National Drug Code Directory:0065-0643-05
Drugs Product Database (DPD):2241209
PubChem Substance:46507662
PubChem Compound:36294
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|
| CASRN | 32986-56-4
|
| prefixIRI | obo2:dinto_DB00684
|
| SMILES | NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O
|
| may interact with |
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| InChI | InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1
|
| DBBrand |
nebramycin 6
aktob
nebramycin
nebcin
tobramaxin
tenebrimycin
nf 6
tobrex
gernebcin
distobram
tobradistin
tenemycin
nebramycin vi
sybryx
obramycin
tobrasone
tobramitsetin
tobramycetin
obracin
tobi
nebramycin factor 6
nebramycin factir 6
tobracin
tobradex
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| subClassOf |
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