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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB00650
http://purl.obolibrary.org/obo/dinto_DB00650
|
|---|---|
| Preferred Name | leucovorin |
| Synonyms |
C20H23N7O7
(2R)-2-[(4-{[(2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | leucovorin
|
|---|---|
| label | leucovorin
|
| DBSynonym |
folinic acid calcium salt usp27
leucovorin calcium
folinic acid
l-leucovorin
calcium folinate
folinic acid calcium salt
leucovorin folinic acid
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|
| ATCCode | V03AF03
|
| Definition | The active metabolite of folic acid. Leucovorin is used principally as its calcium salt as an antidote to folic acid antagonists which block the conversion of folic acid to folinic acid. [PubChem]
|
| has effect |
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| has pharmacological target | |
| inhibits | |
| type | |
| InChIKey | InChIKey=VVIAGPKUTFNRDU-ZGTCLIOFSA-N
|
| AHFScode | 92:00.00
|
| Synonym | C20H23N7O7
(2R)-2-[(4-{[(2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
|
| xref |
PharmGKB:PA450198
PubChem Substance:46505436
ChemSpider:49292
PubChem Compound:54575
Drugs.com:http://www.drugs.com/cdi/leucovorin.html
Drugs Product Database (DPD):2182998
Wikipedia:http://en.wikipedia.org/wiki/Leucovorin
National Drug Code Directory:0555-0484-18
RxList:http://www.rxlist.com/cgi/generic/leucovorin.htm
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| CASRN | 1492-18-8
|
| prefixIRI | obo2:dinto_DB00650
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| is transported by | |
| SMILES | NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
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| may interact with | |
| InChI | InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12?,13-/m1/s1
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| DBBrand |
calcium citrovorum factor
leucal
folinic acid-sf
wellcovorin
citrovorum factor
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |