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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB00624
http://purl.obolibrary.org/obo/dinto_DB00624
|
|---|---|
| Preferred Name | testosterone |
| Synonyms |
(1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
C19H28O2
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | testosterone
|
|---|---|
| label | testosterone
|
| DBSynonym |
testosteronum [inn-latin]
testosterone enanthate
testosterona [inn-spanish]
testostosterone
testosterone hydrate
testosteron
trans-testosterone
testosterone cypionate
tes
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| ATCCode |
G03BA03
G03EK01
G03BA02
|
| Definition | Testosterone is a steroid sex hormone found in both men and women. In men, testosterone is produced primarily by the Leydig (interstitial) cells of the testes when stimulated by luteinizing hormone (LH). It functions to stimulate spermatogenesis, promote physical and functional maturation of spermatozoa, maintain accessory organs of the male reproductive tract, support development of secondary sexual characteristics, stimulate growth and metabolism throughout the body and influence brain development by stimulating sexual behaviors and sexual drive. In women, testosterone is produced by the ovaries (25%), adrenals (25%) and via peripheral conversion from androstenedione (50%). Testerone in women functions to maintain libido and general wellbeing. Testosterone exerts a negative feedback mechanism on pituitary release of LH and follicle-stimulating hormone (FSH). Testosterone may be further converted to dihydrotestosterone or estradiol depending on the tissue.
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| has effect |
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| has pharmacological target | |
| induces | |
| activates | |
| inhibits | |
| type | |
| InChIKey | InChIKey=MUMGGOZAMZWBJJ-DYKIIFRCSA-N
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| is metabolised by |
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| AHFScode | 68:08.00
|
| Synonym | (1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
C19H28O2
|
| xref |
Guide To Pharmacology:2858
ChEBI:17347
RxList:http://www.rxlist.com/cgi/generic2/androgel.htm
Wikipedia:http://en.wikipedia.org/wiki/Testosterone
IUPHAR:2858
National Drug Code Directory:0051-8488-88
PDB:DHT
PubChem Compound:6013
Drugs Product Database (DPD):2246063
PharmGKB:PA451627
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/tes1438.shtml
PubChem Substance:46505691
ChemSpider:5791
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| CASRN | 58-22-0
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| prefixIRI | obo2:dinto_DB00624
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| is transported by | |
| related with | |
| SMILES | [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C
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| may interact with | |
| InChI | InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1
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| DBBrand |
testim
testro aq
testoderm tts
orquisteron
percutacrine androgenique
relibra
androsorb
sustanon
testoject-50
oreton f
testolin
andronate 100
testoviron t
andriol
testrone
oreton
virormone
andryl 200
sustanone
neo-hombreol f
libigel
everone 200
oreton-f
androgel
malestrone
testamone 100
testrin-p.a
testandrone
testiculosterone
t-cypionate
bio-t-gel
andronate 200
andronaq
teslen
androderm
primoteston
methyltestosterone
cristerona t
testaqua
neotestis
testoviron schering
synandrol f
striant
testopropon
metandren
androlin
andrusol
testopel pellets
primotest
perandren
testobase
virosterone
malerone
oreton methyl
cristerone t
mertestate
testosteroid
testogel
andropatch
neo-testis
testoderm
andropository 200
testryl
testoviron
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| subClassOf |
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