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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB00616
http://purl.obolibrary.org/obo/dinto_DB00616
|
|---|---|
| Preferred Name | candoxatril |
| Synonyms |
(1s,4s)-4-({1-[(2S)-3-(2,3-dihydro-1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentane}amido)cyclohexane-1-carboxylic acid
C29H41NO7
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | candoxatril
|
|---|---|
| label | candoxatril
|
| Definition | Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), the active enantiomer of candoxatrilat (UK-69578), a potent neutral endopeptidase (NEP) inhibitor used in the treatment of chronic heart failure.
|
| has pharmacological target | |
| inhibits | |
| type | |
| InChIKey | InChIKey=ZTWZVMIYIIVABD-OEMFJLHTSA-N
|
| Synonym | (1s,4s)-4-({1-[(2S)-3-(2,3-dihydro-1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentane}amido)cyclohexane-1-carboxylic acid
C29H41NO7
|
| xref |
ChEBI:3353
PharmGKB:PA164764517
BindingDB:50084625
|
| CASRN | 118785-03-8
|
| prefixIRI | obo2:dinto_DB00616
|
| SMILES | COCCOC[C@H](CC1(CCCC1)C(=O)N[C@H]1CC[C@H](CC1)C(O)=O)C(=O)OC1=CC2=C(CCC2)C=C1
|
| InChI | InChI=1S/C29H41NO7/c1-35-15-16-36-19-23(27(33)37-25-12-9-20-5-4-6-22(20)17-25)18-29(13-2-3-14-29)28(34)30-24-10-7-21(8-11-24)26(31)32/h9,12,17,21,23-24H,2-8,10-11,13-16,18-19H2,1H3,(H,30,34)(H,31,32)/t21-,23-,24+/m0/s1
|
| DBBrand | candoxatrilat
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |