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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB00596
http://purl.obolibrary.org/obo/dinto_DB00596
|
|---|---|
| Preferred Name | halobetasol propionate |
| Synonyms |
(1R,8S,13S,14R)-14-(2-chloroacetyl)-1,8-difluoro-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-14-yl propanoate
C25H31ClF2O5
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | halobetasol propionate
|
|---|---|
| label | halobetasol propionate
|
| ATCCode | D07AC21
|
| Definition | Halobetasol propionate is thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. It is used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
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| has pharmacological target | |
| activates | |
| type | |
| InChIKey | InChIKey=BDSYKGHYMJNPAB-YKQIDFLYSA-N
|
| AHFScode | 84:06.00
|
| Synonym | (1R,8S,13S,14R)-14-(2-chloroacetyl)-1,8-difluoro-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-14-yl propanoate
C25H31ClF2O5
|
| xref |
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/ult1649.shtml
National Drug Code Directory:0713-0639-15
PubChem Compound:48175
RxList:http://www.rxlist.com/cgi/generic3/halobetasol.htm
Drugs Product Database (DPD):1962701
ChemSpider:43819
PharmGKB:PA164768832
Drugs.com:http://www.drugs.com/cdi/halobetasol-cream.html
PubChem Substance:46506187
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| CASRN | 66852-54-8
|
| prefixIRI | obo2:dinto_DB00596
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| related with | |
| SMILES | [H][C@]1(F)CC2C3C[C@H](C)[C@](OC(=O)CC)(C(=O)CCl)C3(C)CC(O)[C@]2(F)C2(C)C=CC(=O)C=C12
|
| InChI | InChI=1S/C25H31ClF2O5/c1-5-21(32)33-25(20(31)12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15?,16?,18-,19?,22?,23?,24-,25-/m0/s1
|
| DBBrand |
ultravate
ulobetasol propionate
halobetasol
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| subClassOf |
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