The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Id http://purl.obolibrary.org/obo/dinto_DB00552
http://purl.obolibrary.org/obo/dinto_DB00552
Preferred Name

pentostatin
Synonyms
(8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H,6H,7H,8H-imidazo[4,5-d][1,3]diazepin-8-ol
C11H16N4O4
Type http://www.w3.org/2002/07/owl#Class

All Properties

prefLabel
pentostatin
label
pentostatin
DBSynonym
2'-dcf
deoxycoformycin
2'-dexoycoformycin
2'-deoxycoformycin
ATCCode
L01XX08
Definition
A potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity. [PubChem]
has pharmacological target
inhibits
type
InChIKey
InChIKey=FPVKHBSQESCIEP-JQCXWYLXSA-N
Synonym
(8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H,6H,7H,8H-imidazo[4,5-d][1,3]diazepin-8-ol
C11H16N4O4
xref
Wikipedia:http://en.wikipedia.org/wiki/Pentostatin
PharmGKB:PA450863
Drugs Product Database (DPD):2011247
PubChem Compound:439693
ChemSpider:37371
PubChem Substance:46507116
BindingDB:50003603
National Drug Code Directory:0409-0801-01
Drugs.com:http://www.drugs.com/cdi/pentostatin.html
See more
See less
CASRN
53910-25-1
prefixIRI
obo2:dinto_DB00552
SMILES
OC[C@H]1O[C@H](C[C@@H]1O)N1C=NC2=C1N=CNC[C@H]2O
may interact with
InChI
InChI=1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9+/m0/s1
DBBrand
co-vidarabine
co-v
pd-adi
vira a deaminase inhibitor
nipent
vidarbine
covidarabine
See more
See less
subClassOf
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display