Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB00514
http://purl.obolibrary.org/obo/dinto_DB00514
|
|---|---|
| Preferred Name | dextromethorphan |
| Synonyms |
(1R,9R,10R)-4-methoxy-17-methyl-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2,4,6-triene
C18H25NO
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | dextromethorphan
|
|---|---|
| label | dextromethorphan
|
| DBSynonym |
dextromethorphan bromhydrate
levometorfano [inn-spanish]
dexyromethorphan
levomethorphan [ban:dcf:inn]
l-methorphan
dextrometorfano [inn-spanish]
dextromethorfan [czech]
dextrometorphan
demorphan
dextromorphan
d-methorphan hydrobromide
destrometerfano [dcit]
demorphine
demorphan hydrobromide
levomethorphane [inn-french]
dextromethorphan bromide
delta-methorphan
d-methorphan
levomethorphanum [inn-latin]
levomethorphan
See more
See less
|
| ATCCode | R05DA09
|
| Definition | The d-isomer of the codeine analog of levorphanol. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (receptors, N-methyl-D-aspartate) and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity. [PubChem]
|
| has pharmacological target | |
| activates | |
| inhibits | |
| type | |
| InChIKey | InChIKey=MKXZASYAUGDDCJ-CGTJXYLNSA-N
|
| is metabolised by |
See more
See less
|
| blocks | |
| AHFScode |
48:16.00
48:08.00
|
| Synonym |
(1R,9R,10R)-4-methoxy-17-methyl-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2,4,6-triene
C18H25NO
|
| xref |
National Drug Code Directory:63824-171-63
Drugs.com:http://www.drugs.com/dextromethorphan.html
Wikipedia:http://en.wikipedia.org/wiki/Dextromethorphan
ChEBI:4470
PharmGKB:PA449273
Drugs Product Database (DPD):816000
See more
See less
|
| CASRN | 125-71-3
|
| prefixIRI | obo2:dinto_DB00514
|
| SMILES | [H][C@@]12CCCC[C@@]11CCN(C)[C@@H]2CC2=C1C=C(OC)C=C2
|
| may interact with |
See more
See less
|
| InChI | InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m0/s1
|
| DBBrand |
hihustan m.
trocal
novahistine dm
creo-terpin
methorate hydrobromide
triaminic dm long lasting for children
benylin pediatric cough suppressant
delsym
romilar
dormethan
robitussin pediatric cough suppressant
hold dm
robitussin maximum strength cough suppressant
benylin adult formula cough suppressant
cosylan
tusilan
koffex dm
balminil dm
benylin dm for children 12 hour
diabe-tuss dm syrup
novahistex dm
metrorat
robitussin pediatric
calmylin #1
benylin dm for children
cough-x
balminil dm children
medicon
pertussin cs children's strength
vicks 44 cough relief
canfodion
pertussin dm extra strength
sucrets 4 hour cough suppressant
benylin dm 12 hour
benylin dm
delsym cough formula
antussan
methorphan
tussade
dormetan
See more
See less
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |