The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

nitazoxanide
Synonyms

C12H9N3O5S

2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate

ID

http://purl.obolibrary.org/obo/dinto_DB00507

ATCCode

P01AX11

binds

http://purl.obolibrary.org/obo/dinto_0945

CASRN

55981-09-4

DBBrand

phavic-1

alinia

DBSynonym

2-(acetolyloxy)-n-(5-nitro-2-thiazolyl)benzamide

nitazoxanid

nitazoxanidum [inn-latin]

tizoxanide glucuronide

2-acetyloxy-n-[(5-nitro-2-thiazolyl)]benzamide

nitazoxanida [inn-spanish]

Definition

Nitazoxanide, also known by the brand name Alinia, is a synthetic nitrothiazolyl-salicylamide derivative and an anti-protozoal agent. It is approved for treatment of infectious diarrhea caused by Cryptosporidium parvum and Giardia lamblia in patients 1 year of age and older. Following oral administration it is rapidly hydrolyzed to its active metabolite, tizoxanide, which is 99% protein bound. Peak concentrations are observed 1?4 hours after administration. It is excreted in the urine, bile and feces. Untoward effects include abdominal pain, vomiting and diarrhea. [Wikipedia]

has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000902

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0001186

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0000317

http://purl.obolibrary.org/obo/OAE_0001280

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000403

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0000517

http://purl.obolibrary.org/obo/OAE_0000434

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0001381

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0000473

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000508

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000275

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000394

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000350

has pharmacological target

http://purl.obolibrary.org/obo/dinto_0945

InChI

InChI=1S/C12H9N3O5S/c1-7(16)20-9-5-3-2-4-8(9)11(17)14-12-13-6-10(21-12)15(18)19/h2-6H,1H3,(H,13,14,17)

InChIKey

InChIKey=YQNQNVDNTFHQSW-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_0945

label

nitazoxanide

prefixIRI

obo2:dinto_DB00507

prefLabel

nitazoxanide

SMILES

CC(=O)OC1=CC=CC=C1C(=O)NC1=NC=C(S1)[N+]([O-])=O

Synonym

C12H9N3O5S

2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate

xref

Drugs.com:http://www.drugs.com/cdi/nitazoxanide.html

PubChem Compound:41684

ChemSpider:38037

PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/ali1659.shtml

Wikipedia:http://en.wikipedia.org/wiki/Nitazoxanide

National Drug Code Directory:67546-111-12

PubChem Substance:46507813

RxList:http://www.rxlist.com/cgi/generic/alinia.htm

BindingDB:50182652

PharmGKB:PA164754874

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/DRON_00015413 DRON LOOM
http://purl.obolibrary.org/obo/DRON_00015413 PDRO LOOM
http://purl.obolibrary.org/obo/DRON_00015413 INBANCIDO LOOM
http://purl.obolibrary.org/obo/DRON_00015413 COVID-19 LOOM
http://purl.obolibrary.org/obo/DRON_00015413 DDSS LOOM
http://purl.obolibrary.org/obo/DRON_00015413 CIDO LOOM
http://purl.obolibrary.org/obo/DRON_00015413 DRON LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000769610 PDQ LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47637 NCIT LOOM
http://purl.bioontology.org/ontology/RXNORM/31819 RXNORM LOOM
http://stirdf.jst.go.jp/id/200907029295039734 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C041747 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0068788 OCHV LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148784 INBANCIDO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148784 CIDO LOOM
http://purl.bioontology.org/ontology/ATC/P01AX11 ATC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#14501 OCHV LOOM
http://purl.obolibrary.org/obo/NCIT_C47637 BERO LOOM
http://purl.bioontology.org/ontology/LNC/LP172569-8 LOINC LOOM
http://purl.jp/bio/4/id/200906047360235966 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148784 NDFRT LOOM
http://purl.obolibrary.org/obo/ARO_3007178 ARO LOOM
http://purl.bioontology.org/ontology/MESH/C041747 MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4021365 VANDF LOOM
https://go.drugbank.com/drugs/DB00507 MDM LOOM
http://purl.bioontology.org/ontology/LNC/MTHU046349 LOINC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026691 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/NDDF/006303 NDDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/407148001 SNOMEDCT LOOM