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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB00365
http://purl.obolibrary.org/obo/dinto_DB00365
|
|---|---|
| Preferred Name | grepafloxacin |
| Synonyms |
C19H22FN3O3
1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | grepafloxacin
|
|---|---|
| label | grepafloxacin
|
| ATCCode | J01MA11
|
| Definition | Grepafloxacin hydrochloride (Raxar and reg;, Glaxo Wellcome) is an oral broad-spectrum quinoline antibacterial agent used to treat bacterial infections. Grepafloxacin was withdrawn in the United States due to its side effect of lengthening the QT interval on the electrocardiogram, leading to cardiac events and sudden death. [Wikipedia]
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| has pharmacological target | |
| inhibits | |
| type | |
| InChIKey | InChIKey=AIJTTZAVMXIJGM-UHFFFAOYSA-N
|
| is metabolised by | |
| Synonym | C19H22FN3O3
1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
|
| xref |
RxList:http://www.rxlist.com/cgi/generic2/grepa.htm
ChemSpider:65391
BindingDB:50117924
Drugs Product Database (DPD):2237735
PharmGKB:PA449812
PubChem Compound:72474
Wikipedia:http://en.wikipedia.org/wiki/Grepafloxacin
PubChem Substance:46507253
Drugs.com:http://www.drugs.com/mtm/grepafloxacin.html
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| CASRN | 119914-60-2
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| prefixIRI | obo2:dinto_DB00365
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| is transported by | |
| SMILES | CC1CN(CCN1)C1=C(F)C(C)=C2C(=O)C(=CN(C3CC3)C2=C1)C(O)=O
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| may interact with |
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| InChI | InChI=1S/C19H22FN3O3/c1-10-8-22(6-5-21-10)15-7-14-16(11(2)17(15)20)18(24)13(19(25)26)9-23(14)12-3-4-12/h7,9-10,12,21H,3-6,8H2,1-2H3,(H,25,26)
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| DBBrand | raxar
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| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |