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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
Acronym | DINTO |
Visibility | Public |
Description | DINTO is an OWL ontology that systematically organizes all drug-drug interaction (DDI) related information. Drug-drug interactions (DDIs) form a significant risk group for adverse effects associated with pharmaceutical treatment. These interactions are often reported in the literature, however, they are sparsely represented in machine-readable resources, such as online databases, thesauri or ontologies. DINTO is an ontology that describes and categorizes DDIs and all the possible mechanisms that can lead to them (including both pharmacodynamic and pharmacokinetic DDI mechanisms). |
Status | Retired |
Format | OWL |
Contact | Maria Herrero, maria.herrero@kcl.ac.uk |
Categories | Health |
Version | Released | Uploaded | Downloads |
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1.3 (Parsed, Indexed, Metrics, Annotator) | 08/26/2015 | 02/11/2016 | OWL | CSV | RDF/XML | Diff |
1.2 (Archived) | 08/26/2015 | 10/14/2015 | OWL | Diff |
1.2 (Archived) | 06/16/2015 | 06/16/2015 | OWL | Diff |
1.2 (Archived) | 06/16/2015 | 06/16/2015 | OWL | Diff |
1 (Archived) | 06/24/2014 | 03/18/2015 | OWL |
more... |
No views of DINTO available
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Id | http://purl.obolibrary.org/obo/dinto_DB00324
http://purl.obolibrary.org/obo/dinto_DB00324
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Preferred Name | fluorometholone |
Synonyms |
C22H29FO4
(1R,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
label | fluorometholone
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prefLabel | fluorometholone
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is metabolised by | |
Definition | A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
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DBBrand |
loticort
efflumidex
trilcin
cortilet
fml forte
fluor-op
ursnon
fml liquifilm
flumetholon
delmeson
oxylone
flarex
fluaton
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ATCCode |
C05AA06
D07XB04
S01BA07
S01CB05
D10AA01
D07AB06
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modulates | |
SMILES | [H][C@@]12CC[C@](O)(C(C)=O)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](C)C2=CC(=O)C=C[C@]12C
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InChI | InChI=1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1
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CASRN | 426-13-1
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prefixIRI | obo2:dinto_DB00324
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Synonym | C22H29FO4
(1R,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
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has effect |
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binds | |
InChIKey | InChIKey=FAOZLTXFLGPHNG-KNAQIMQKSA-N
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subClassOf | |
related with | |
induces | |
is substrate of | |
type | |
xref |
Drugs Product Database (DPD):2238568
PubChem Substance:46505984
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/fml1183.shtml
PubChem Compound:9878
Wikipedia:http://en.wikipedia.org/wiki/Fluorometholone
National Drug Code Directory:11980-228-05
RxList:http://www.rxlist.com/cgi/generic/fluorometholone.htm
Drugs.com:http://www.drugs.com/cdi/fluorometholone.html
ChemSpider:9494
PharmGKB:PA164781355
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DBSynonym |
fluormetholone
fluoromethalone
fml
fluormetholon
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activates | |
AHFScode | 52:08.08
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has pharmacological target |
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Add NCBO Web Widgets to your site for DINTO
Widget type | Widget demonstration |
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Step 2: Follow the Instructions
For more help visit NCBO Widget Wiki |
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Example 1 (start typing the class name to get its full URI)
Example 2 (get the ID for a class) Example 3 (get the preferred name for a class) Step 2: Follow the Instructions
For more help visit NCBO Widget Wiki |
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Step 2: Follow the InstructionsCopy the code below and paste it to your HTML page <iframe frameborder="0" src="/widgets/visualization?ontology=DINTO&class=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FOAE_0001661&apikey=YOUR_API_KEY"></iframe> For more help visit NCBO Widget Wiki |
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Step 2: Follow the InstructionsCopy the code below and paste it to your HTML page <link rel="stylesheet" type="text/css" href="/widgets/jquery.ncbo.tree.css"> <script src="/widgets/jquery.ncbo.tree-2.0.2.js"></script> <div id="widget_tree"></div> var widget_tree = $("#widget_tree").NCBOTree({ apikey: "YOUR_API_KEY", ontology: "DINTO" }); You can also view a detailed demonstration For more help visit NCBO Widget Wiki |